ERYTHROMYCIN ETHYLSUCCINATE 250 mg - LENNON Granules for Suspension
Country: South Africa
Language: English
Source: South African Health Products Regulatory Authority (SAHPRA)
Patient Information leaflet
(PIL)
24-04-2024
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Patient Information leaflet
ERYTHROMYCIN ETHYLSUCCINATE 125 mg - LENNON Granules for Suspension
ERYTHROMYCIN ETHYLSUCCINATE 250 mg - LENNON Granules for Suspension
SCHEDULING STATUS:
S4
PROPRIETARY NAME
(and dosage form):
ERYTHROMYCIN ETHYLSUCCINATE 125 mg - LENNON Granules for Suspension
ERYTHROMYCIN ETHYLSUCCINATE 250 mg - LENNON Granules for Suspension
COMPOSITION:
Each 5 mL of the reconstituted suspension contains:
(1) Erythromycin ethylsuccinate equivalent to 125 mg
erythromycin
base
(2) Erythromycin ethylsuccinate equivalent to 250 mg erythromycin base
Preserved with: 0,03% m/v propylhydroxybenzoate sodium 0,06% m/v methyl hydroxybenzoate sodium
PHARMACOLOGICAL CLASSIFICATION:
A 20.1.1 Broad and medium spectrum antibiotics.
PHARMACOLOGICAL ACTION:
Erythromycin has
bacteriostatic
activities with a range of antimicrobial action which is similar to that of penicillin G. It is
active against some Gram-positive bacteria, some Gram-negative bacteria (Neisseria and Haemophilus), spirochaetes,
some rickettsias, Streptococcus pneumoniae, haemolytic streptococci, and corynebacteria. Staphylococci (including
those resistant to penicillin) are rather less sensitive. During prolonged treatment of infections, the development of
resistant strains is common.
INDICATIONS:
Erythromycin is an agent for use in individuals unable to take penicillin because of previous reactions. Pharyngitis,
Scarlet Fever anderysipelas produced by group-A Streptococcus pyogenes respond to erythromycin. Erythromycin is
useful in cases in which the presence of penicillinase-producing staphylococci may be responsible for relapse of
streptococcal pharyngitis after adequate treatment with penicillin G, and other infections due to enterococci may also
respond well to the drug. Erythromycin is effective in eradicating the acute or chronic diphtheria bacillus carrier
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