Country: South Africa
Language: English
Source: South African Health Products Regulatory Authority (SAHPRA)
Lennon
LEN V.K. 250 mg TABLETS LEN V.K. 500 mg TABLETS LEN V.K. 250 SYRUP SCHEDULING STATUS: S4 PROPRIETARY NAME (and dosage form): LEN V.K. 250 mg TABLETS LEN V.K. 500 mg TABLETS LEN V.K. 250 SYRUP COMPOSITION: Each tablet contains the equivalent of 250 mg or 500 mg Phenoxymethylpenicillin as the potassium salt. When dispensed as directed each 5 mL contains the equivalent of 250 mg Phenoxymethylpenicillin as the potassium salt Preservative: Sodium Benzoate 0,1% m/v PHARMACOLOGICAL CLASSIFICATION: A 20.1.2 Penicillins. PHARMACOLOGICAL ACTION: Phenoxymethylpenicillin is a narrow spectrum penicillin, inhibited by penicillinase. It has an antimicrobial spectrum similar to benzylpenicillin for aerobic Gram + organisms. Itis more stable in acidic medium than benzylpenicillin and is therefore better absorbed from the gastro-intestinal tract. Once absorbed it is widely distributed throughout the body, and normally rapidly eliminated from the body, mainly by the kidneys. INDICATIONS: Prophylactic: Recurrence of rheumatic fever. Treatment of mild to moderate infections caused by sensitive organisms: Pneumococcal infections of the middle ear; Streptococcal otitis media and sinusitis; Streptococcal pharyngitis caused by Strep pyogenes; mild to moderate pulmonary and periodontal anaerobic infections; gingivostomatitis; early Lyme disease. CONTRA-INDICATIONS: Phenoxymethylpenicillin should not be given to patients known to be allergic to penicillin and should be given with care to patients with a history of allergy to cephalosporins. Cases of cross sensitivity have been reported. It should not be given to babies, in the neonatal period, born of hypersensitive mothers. It is not recommended for chronic, severe or deep- seated infections such as subacute bacterial endocarditis, meningitis or syphilis. WARNINGS: Read the complete document