Land: Taiwan
Språk: kinesiska
Källa: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)
HYDROCHLOROTHIAZIDE (EQ TO 3,4-DIHYDROCHLOROTHIAZIDE);;AMILORIDE HCL
美商默沙東藥廠股份有限公司台灣分公司 台北市信義區信義路五段106號12樓 (86683720)
C03EA01
錠劑
AMILORIDE HCL (4028000110) 5MG; HYDROCHLOROTHIAZIDE (EQ TO 3,4-DIHYDROCHLOROTHIAZIDE) (4028100600) 50MG
瓶裝
製 劑
須由醫師處方使用
FROSST IBERICA S.A. VIA COMPLUTENSE, 140 28805 ALCALA DE HENARES, MADRID, SPAIN ES
hydrochlorothiazide and potassium-sparing agents
高血壓
註銷日期: 2016/05/24; 註銷理由: 許可證已逾有效期; 有效日期: 2014/08/27; 英文品名: MODURETIC TABLETS
已註銷
1993-02-06
MK0870ATWN-2013-007251 IPC-MK0870A-MF-102009 Tablets MODURETIC ® (hydrochlorothiazide 50 mg and amiloride HCl 5 mg, MSD) MODURETIC® (hydrochlorothiazide and amiloride HCl, MSD) is a diuretic/antihypertensive combining the potent natriuretic action of hydrochlorothiazide with the potassium-conserving property of amiloride HCl. MODURETIC provides diuretic and antihypertensive activity (principally due to the hydrochlorothiazide component), while acting through the amiloride component to prevent the excessive potassium loss that may occur in patients receiving a thiazide diuretic. Due to its amiloride component, the urinary excretion of magnesium is less with MODURETIC than with a thiazide or loop diuretic used alone. The mild diuretic and antihypertensive actions of amiloride HCl are additive to the natriuretic, diuretic and antihypertensive activity of the thiazide while minimizing the loss of potassium and bicarbonate and lessening the likelihood of acid-base imbalance. The onset of the diuretic action of MODURETIC is within 2 hours and this action appears to be sustained for approximately 24 hours. HYDROCHLOROTHIAZIDE Hydrochlorothiazide is an orally effective diuretic and antihypertensive. Onset of action following oral administration of hydrochlorothiazide occurs in 2 hours and reaches a peak effect in about 4 hours. The diuretic activity persists for approximately 6 to 12 hours. Hydrochlorothiazide does not affect normal blood pressure. AMILORIDE HCl Amiloride HCl is a potassium-conserving drug which possesses mild natriuretic, diuretic, and antihypertensive activity. The principal use is to conserve potassium in patients receiving diuretic agents in whom excessive potassium losses occur or are expected. Amiloride HCl usually begins to act within 2 hours after an oral dose. Its effect on electrolyte excretion reaches a peak between 6 and 10 hours and lasts about 24 hours. Peak plasma levels are obtained in 3 to 4 hours and the plasma half-life varies from 6 to 9 hours. INDICATIONS MODURETIC is indicated in Läs hela dokumentet