亞翠佩膜衣錠

国家: 台湾

语言: 中文

来源: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

有效成分:

EFAVIRENZ;;EMTRICITABINE;;TENOFOVIR DISOPROXIL FUMARATE

可用日期:

香港商吉立亞醫藥有限公司台灣分公司 臺北市信義區松仁路32號10樓之1、36號10樓之1 (54376860)

ATC代码:

J05AR06

药物剂型:

膜衣錠

组成:

主成分 () ; EFAVIRENZ (0818001700) MG; TENOFOVIR DISOPROXIL FUMARATE (0818003510) MG; EMTRICITABINE (0818003700) MG

每包单位数:

塑膠瓶裝

类:

製　劑

处方类型:

須由醫師處方使用

厂商:

GILEAD SCIENCES INC. 333 LAKESIDE DRIVE, FOSTER CITY, CALIFORNIA(CA) 94404, USA US

治疗领域:

emtricitabine, tenofovir disoproxil and efavirenz

疗效迹象:

ATRIPLA適合做為一種完整的治療配方或者與其他抗反轉錄病毒藥物合併使用，用於治療成人HIV-1感染。

產品總結:

有效日期: 2025/06/08; 英文品名: ATRIPLA TABLETS

授权日期:

2010-06-08

资料单张

B
HIV-1
HBV
emtricitabine FTC
/
tenofovir disoproxil fumarate
TDF
ATRIPLA
B
HBV
HIV-I
HBV
ATRIPLA
B
5.1
1
ATRIPLA
HIV-1
2
2.1
ATRIPLA
ATRIPLA
B
HBV
5.1
ATRIPLA
5.7
ATRIPLA
5.3
ATRIPLA
5.8
8.18.3
2.2
ATRIPLA
600
efavirenz
EFV
200
emtricitabine FTC
300
tenofovir disoproxil fumarate TDF
ATRIPLA
12.3
ATRIPLA
18
2.3
ATRIPLA
50 mL /min
8.6
2.4
ATRIPLA
Child-Pugh B
C
5.3
8.7
2.5
RIFAMPIN
50
ATRIPLA
rifampin
ATRIPLA
200 mg /day
efavirenz
7.3
12.3
3
ATRIPLA
123
efavirenz 600 mg
emtricitabine 200 mg
tenofovir disoproxil fumarate 300 mg
tenofovir disoproxil 245 mg
4
• ATRIPLA
ATRIPLA
efavirenz
–
5.2
• ATRIPLA
voriconazole
elbasvir/grazoprevir
7.3
12.3
5
5.1
HIV-1
HBV
B
B
2.1
HBV
HIV
FTC
TDF
ATRIPLA
B
HIV-I
HBV
ATRIPLA
B
5.2
600 mg EFV
26% 266/1,008
17% 111/635
EFV
0.9% 9/1,008
EFV
4
–
0.1%
EFV
2
11
EFV
1
16
1.7% 17/1,008
ATRIPLA
ATRIPLA
/
–
4
NNRTI
EFV
19
nevirapine
EFV
9
EFV
2
59/182
32%
EFV
6.1
2
3
4
4
28
3-1,642
ATRIPLA
5.3
EFV ATRIPLA
B
C
5.1
ATRIPLA
ATRIPLA
6.2
8.7
2.1
ATRIPLA
酶
ATRIPLA
6.1
5.4
ATRIPLA
4
7.3
•
ATRIPLA
•
ATRIPLA
EFV
QTc
7.1
12.2
Torsade de Pointes
ATRIPLA
3
ATRIPLA
ATRIPLA
2.5
4
7
5.5
EFV ATRIPLA
1,008
EFV
2.1
635
1.5
EFV
2.4%, 0.9%
0.7%, 0.3%
0.5%,
0%
0.4%, 0.5%
0.4%, 0.3%
0.2%, 0.3%
AI266006 006, NCT00002410
1,266
EFV
3
；
EFV+zidovudine+lamivudine
EFV+indinavir
indinavir+zidovudine+lamivudine
180
102
76
EFV
EFV
study 006
EFV
EFV
1%
EFV
EFV
EFV
6
5.6
EFV
53% 531/1,008
25% 156/635
1,008
28.1%
1%
8.3%
7.0%
6.2%
1.2%
50.7%
2.0%
2.1%
EFV
5% 9%
3% 5%
5.5
2
006
24
EFV
indinavir
ATRIPLA
5.7
Emtricitabine
tenofovir
EFV
TDF ATRIPLA
Fanconi syndrome
6.2
ATRIPLA
ATRIPLA
50 mL /min
[
NSAIDs
]
ATRIPLA
7.2
TDF
HIV
NSAIDs
NSAIDs
/
ATRIPLA
5.8
–
efavi
renz
ATRIPLA
ATRIPLA
12
2.1
8.1, 8.3
5.9
HIV-1
TDF ATRIPLA
BMD
TDF
1,25
D
TDF
BMD
BMD
D VitD
TDF
6.2
TDF
5.7
5.10
EFV
phenytoin
phenobarbital
7.3
5.11
/
苷
TDF
FTC
ATRIPLA
ATRIPLA
5.12
ATRIPLA
Mycobacterium avium
Pneumocystis jirovecii
PCP
Graves
Gui
llain-Barré
5.13
EFV
cushingoid appearance
6
•
HIV-1
HBV
B
5.1
•
5.2
•
5.3
5.5
•
5.6
•
5.7