Страна: Малайзия
Език: английски
Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Glucosamine Sulfate Potassium Chloride; CHONDROITIN SULFATE SODIUM
IDAMAN PHARMA MANUFACTURING SDN BHD
Glucosamine Sulfate Potassium Chloride; CHONDROITIN SULFATE SODIUM
60 Capsules; 90 Capsules; 60 Capsules; 90 Capsules
IDAMAN PHARMA MANUFACTURING SDN BHD
CITREX GLUCOSAMINE CHONDROITIN CAPSULE Glucosamine Sulfate Potassium Chloride 497.50mg equivalent to 375mg Glucosamine Sulfate & Chondroitin Sulfate Sodium (200mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What Citrex Glucosamine Chondroitin Capsule is used for 2. How Citrex Glucosamine Chondroitin Capsule works 3. Before you use Citrex Glucosamine Chondroitin Capsule 4. How to use Citrex Glucosamine Chondroitin Capsule 5. While you are using it 6. Side Effects 7. Storage and Disposal of Citrex Glucosamine Chondroitin Capsule 8. Product Description 9. Product Registration Holder and Manufacturer 10. Date of Revision WHAT CITREX GLUCOSAMINE CHONDROITIN CAPSULE IS USED FOR As an adjuvant for therapy for osteoarthritis (OA) only. HOW CITREX GLUCOSAMINE CHONDROITIN CAPSULE WORKS Glucosamine is a natural substance found in chitin, mucoproteins, and mucopolysaccharides. It is involved in the manufacture of glycosaminoglycan, which forms cartilage tissue in the body; glucosamine is also present in tendons and ligaments.Glucosamine must be synthesised by the body but the ability to do this declines with age. Glucosamine and its salts have therefore been advocated in the treatment of rheumatic disorders including osteoarthritis. Glucosamine also acts to improve the viscosity of synovial fluid by increasing synovial fluid production, thereby providing lubricant activity. Chondroitin sulphate is vital for the structure and function of articular cartilage. Chondroitin sulphate is an important component of aggrecan which is found in articular cartilage. Aggrecan confers upon articular cartilage shock-absorbing properties. It does this by providing cartilage with a swelling pressure that is restrained by the tensile force of collagen fibers. This balance confers upon articular cartilage the deformable resilience vital to its function. BEFORE YOU USE CITREX GLUCOSAMINE CHONDROITIN CAPSULE - _When you must not use it _ You must not take Citrex Glucosamine Chondroitin Capsule and should talk t Прочетете целия документ
IDAMAN PHARMA MANUFACTURING CITREX GLUCOSAMINE CHONDROITIN CAPSULE DESCRIPTION Clean, uniform, dry, telescope type hard gelatin capsules. Capsules are shiny and not smudged or sticky. Grey color capsule. Content of capsule: Each capsule contains Glucosamine Sulfate 375mg and Chondroitin Sulfate Sodium 200mg. Off-white to yellowish in colour. ACTIVE SUBSTANCE(S) • Glucosamine sulfate potassium chloride 497.50mg equivalent to 375mg glucosamine sulfate. • Chondroitin sulfate sodium 200mg. SOURCE • Glucosamine sulfate potassium chloride : Sea Shrimp/ Crab shell source • Chondroitin sulfate sodium : Bovine source • Capsule : Bovine source PHARMACODYNAMICS Glucosamine is a natural substance found in chitin, mucoproteins, and mucopolysaccharides. It is involved in the manufacture of glycosaminoglycan, which forms cartilage tissue in the body; glucosamine is also present in tendons and ligaments. Glucosamine must be synthesised by the body but the ability to do this declines with age. Glucosamine and its salts have therefore been advocated in the treatment of rheumatic disorders including osteoarthritis. Glucosamine also acts to improve the viscosity of synovial fluid by increasing synovial fluid production, thereby providing lubricant activity. Chondroitin sulphate is vital for the structure and function of articular cartilage. Chondroitin sulphate is an important component of aggrecan which is found in articular cartilage. Aggrecan confers upon articular cartilage shock-absorbing properties. It does this by providing cartilage with a swelling pressure that is restrained by the tensile force of_ _ collagen fibers. This balance confers upon articular cartilage the deformable resilience vital to its function. PHARMACOKINETICS _Absorption _ After oral administration, bioavailability is low due to first-pass hepatic metabolism ~26%. The gastrointestinal absorption is close to 90%. _ _ _Distribution _ Glucosamine is not protein-bound, but rather incorporates into plasma proteins (primarily globulins). Volume of Dis Прочетете целия документ