Страна: Малайзия
Език: английски
Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
FERROUS FUMARATE
IDAMAN PHARMA MANUFACTURING SDN BHD
FERROUS FUMARATE
10 Tablets
IDAMAN PHARMA MANUFACTURING SDN BHD
SOLIDIRON TABLET 200MG Ferrous fumarate (200mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What Solidiron Tablet is used for 2. How Solidiron Tablet _ _ works 3. Before you use Solidiron Tablet 4. How to use Solidiron Tablet 5. While you are using it 6. Side effects 7. Storage and Disposal of Solidiron Tablet 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision 11. Serial Number WHAT SOLIDIRON TABLET_ _IS USED FOR Solidiron Tablet contains a form of iron called ferrous fumarate. Your body needs iron for the normal development of red blood cells. Lack of iron causes a reduction in the number of red blood cells formed in the body and leads to iron deficiency anemia. Solidiron Tablet is used for the prevention and treatment of iron deficiency resulting from: • inadequate iron in the diet. • poor absorption of dietary iron. • iron deficiency in pregnancy. • parasitic infections. • blood loss. HOW SOLIDIRON TABLET_ _WORKS Iron, in the form of ferrous fumarate, is involved in the formation and functioning of red blood cells. BEFORE YOU USE SOLIDIRON TABLET _When you must not use it _ Do not take this medicine if: • you are allergic to ferrous fumarate or any other ingredients of this leaflet. • you have a condition where there is too much iron build-up in the body (hemochromatosis, hemosiderosis). • you have any form of anemia conditions not due to iron deficiency. • there is presence of blood in your urine (paroxysmal nocturnal haemoglobinuria). • you have active peptic ulcer. • you are undergoing repeated blood transfusions • you have inflammatory bowel disease. _ _ _ _ - _Before you start to use it _ Check with your doctor or pharmacist before taking Solidiron Tablet if: • you have undergone abdominal surgery (gastrectomy). • you have microcytic anaemia. • you have metabolic disorders. If you are not sure if any of the above apply to you, talk to your doctor or ph Прочетете целия документ
SOLIDIRON TABLET 200 MG PRODUCT DESCRIPTION Clean, dry, uniform, round, biconvex, even edged tablets and brown in colour. Each tablet contains: Ferrous Fumarate 200mg. PHARMACODYNAMICS Iron is an essential constituent of the body, and is necessary for haemoglobin formation and the oxidative processes of living tissues. Iron and iron salts should be given for the treatment or prophylaxis of iron deficiency anaemias. Preparations of iron are administered by mouth, by intramuscular or intravenous injection. Soluble ferrous salts are most effective by mouth. Ferrous fumarate is an easily absorbed source of iron for replacement therapy. It is a salt of ferrous iron with an organic acid and is less irritant to the gastro-intestinal tract than salts with inorganic acids. PHARMACOKINETICS Absorption Once in the stomach, the acid conditions of the gastric contents cause the dissociation of ferrous fumarate and ferrous ions are liberated. These ions are absorbed through the proximal portion of the duodenum. The ferrous iron absorbed by the mucosal cells of the duodenum is oxidised to the ferric form, and this is bound to protein to form Ferritin. Distribution Ferritin in the mucosal cells releases iron into the blood, where it is bound to transferrin and is passed onto the iron stores in the liver, spleen, and bone marrow. These stores constitute a reserve of iron for synthesis of haemoglobin, myoglobin, and iron containing enzymes. Elimination Iron is lost from the body through loss of cells i.e, urine, faeces, hair, skin, sputum, nails, sloughing of mucosal cells, and through blood loss. Ferrous fumarate has the same pattern of absorption and excretion as dietary iron. INDICATIONS Prophylaxis and treatment of Iron deficiency Solidiron Tablet 200mg is indicated in the prevention and treatment of iron deficiency resulting from inadequate diet, malabsorption, pregnancy, parasitic infestation and/or blood loss. RECOMMENDED DOSE Adult Prophylactic - Oral, 200mg daily. Therapeutic - Oral, 200 mg three or four times a day, the Прочетете целия документ