TP-APRA 500 WSP ApramycinSulphate 500mgg Water Soluble Powder

Страна: Малайзия

Език: английски

Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активна съставка:

APRAMYCIN SULFATE

Предлага се от:

Thye Pharma Sdn. Bhd

INN (Международно Name):

APRAMYCIN SULFATE

Произведено от:

Thye Pharma Sdn. Bhd

Данни за продукта

Veterinary Package Insert
TP-Apra 500 WSP Apramycin Sulphate
500 mg/g Water Soluble Powder
PRODUCT DESCRIPTION
A light yellow or light brown colour powder, which
contains 500 mg/g of apramycin sulphate in 225g
or 450g sachet.
PHARMACODYNAMICS & PHARMACOKINETICS
Apramycin
is
a
broad-spectrum
aminocyclitol
antibiotic produced by a strain of
_Streptomyces _
_tenebrarius_. Apramycin is bactericidal at minimum
inhibitory
concentrations.
Apramycin
is
effective
against
both
Gram-negative
and
Gram-positive
bacteria. It is effective against most field strains of
_Escherichia coli_ and salmonellae.
The oral administration of apramycin is intended for
antimicrobial activity within the gut; apramycin is
poorly absorbed, particularly in older animals:
INDICATION
Treatment
of
bacterial
enteritis
associated
with
organisms
susceptible
to
apramycin
in
pigs,
colibacillosis and salmonellosis in calves _Escherichia _
_coli_ septicaemia in young chickens.
RECOMMENDED DOSAGE AND ADMINISTRATION
The
intake
of
medicated
water
depends
on
the
clinical condition of the animals. In order to obtain
the correct dosage, the concentration of TP-Apra 500
WSP Apramycin Sulphate 500mg/g Water Soluble
Powder has to be adjusted accordingly.
Add the appropriate quantity of the product to 5 – 10
times its own volume of water. Stir well and allow the
solution to stand for a few minutes and then stir
again.
When
completely
dissolved,
add
the
full
volume of drinking water and stir well.
For treatment in pigs, TP-Apra 500 WSP Apramycin
Sulphate 500mg/g Water Soluble Powder should be
administered via the drinking water. Treated pigs
should consume sufficient medicated drinking water
to obtain 7.5 – 12.5 mg apramycin activity per kg of
bodyweight
daily
for
seven
days.
This
may
be
achieved
by
adding
2.4g
of
TP-Apra
500
WSP
Apramycin Sulphate 500mg/g Water Soluble Powder
per 20 litres of water.
As a guide, average daily water consumption for
fattening pigs is shown in the following table:
Bodyweight (kg)
Average
Consumption
(litres)
5
1.10
10
1.75
For trea