দেশ: নিউ জিলণ্ড
ভাষা: ইংরেজি
সূত্র: Medsafe (Medicines Safety Authority)
Colecalciferol 1.25mg equivalent to 50,000 IU (plus 12% (0.15 mg) overage)
PSM Healthcare Ltd trading as API Consumer Brands
Colecalciferol 1.25 mg (= 50,000 IU; plus 12% (0.15 mg) overage)
1.25 mg
Coated tablet
Active: Colecalciferol 1.25mg equivalent to 50,000 IU (plus 12% (0.15 mg) overage) Excipient: Acacia Ammonia solution Calcium carbonate Castor oil Ether Gelatin Hydrated silica Lactose monohydrate Magnesium stearate Maize starch Methylated spirits Povidone Powdered cellulose Prepared theobroma Purified talc Purified water Shellac Sucrose Titanium dioxide White beeswax
Bottle, glass, Amber, with PP cap, 12 tablets
Prescription
Prescription
DSM Nutritional Products France SAS
Indicated for treatment of vitamin D deficiency associated with malabsorption in children and/or adult patients. Indicated for prevention and treatment of vitamin D deficiency states.
Package - Contents - Shelf Life: Bottle, glass, Amber, with PP cap - 12 tablets - 18 months from date of manufacture stored at or below 25°C
1996-04-01
1 DATA SHEET CAL.D.FORTE (Colecalciferol 1.25mg) PRESENTATION Cal.D.Forte Tablets contain 1.25mg of colecalciferol. White, sugar-coated, 8mm, biconvex tablet_. _ USES ACTIONS: Colecalciferol is a vitamin D compound which possesses the property of preventing or treating rickets. Vitamin D is essential for promoting absorption and utilisation of calcium and phosphate and for normal calcification of bone. Along with parathyroid hormone and calcitonin, it regulates serum calcium concentrations by increasing serum calcium and phosphate concentrations as needed. Vitamin D stimulates calcium and phosphate absorption from the small intestine and mobilises calcium from bone. Colecalciferol is transferred to the liver where it is converted to calcifediol (25- hydroxycolecalciferol), which is then transferred to the kidneys and converted to calcitriol (1,25-dihyroxycolecalciferol, thought to be the most active form) and 24,25- dihydroxycolecalciferol (physiologic role not determined). Calcitriol appears to act by binding to a specific receptor in the cytoplasm of the intestinal mucosa and subsequently being incorporated into the nucleus, probably leading to formation of the calcium-binding protein which results in increased absorption of calcium from the intestine. Also, calcitriol may regulate the transfer of calcium ion from bone and stimulate reabsorption of calcium in the distal renal tubule, thereby effecting calcium homeostasis in the extracellular fluid. ONSET OF ACTION – Hypercalcaemic: 12 to 24 hours; therapeutic effect may take 10 to 14 days. DURATION OF ACTION – Following oral administration: up to 6 months; repeated doses have a cumulative action. PHARMACOKINETICS: Vitamin D substances are well absorbed from the gastrointestinal tra সম্পূর্ণ নথি পড়ুন