Dechra TMPS Powder

País: Austràlia

Idioma: anglès

Font: APVMA (Australian Pesticides and Veterinary Medicines Authority)

ingredients actius:

TRIMETHOPRIM; SULFADIMIDINE

Disponible des:

DECHRA VETERINARY PRODUCTS (AUSTRALIA) PTY. LTD.

formulario farmacéutico:

ORAL POWDER, PRE-MIX

Composición:

TRIMETHOPRIM PYRIMIDINE Active 90.0 mg/g; SULFADIMIDINE SULFANYL Active 450.0 mg/g

Unidades en paquete:

250 g; 500 g

clase:

VM - Veterinary Medicine

Área terapéutica:

ANTIBIOTIC & RELATED

Resumen del producto:

Poison schedule: 4; Withholding period: MEAT: (horses) Do not use less than 28 d ays before slaughter for human consumpti on; Host/pest details: HORSE: [ACTINOBACILLUS EQUULI, ESCHERICHIA COLI (E. COLI), PASTEURELLA SPP., SALMONELLA, STAPHYLOCOCCUS AUREUS, STAPHYLOCOCCUS INTERMEDIUS, STREPTOCOCCUS EQUI VAR EQUI, STREPTOCOCCUS ZOOEPIDEMICUS]

Estat d'Autorització:

Registered

Data d'autorització:

2023-07-01

Informació per a l'usuari

Dechra TMPS Powder
89448/124904
Product Name:
APVMA Approval No.:
Label Name:
Dechra TMPS Powder
Signal Headings:
PRESCRIPTION ANIMAL REMEDY
KEEP OUT OF REACH OF CHILDREN
FOR ANIMAL TREATMENT ONLY
Constituent
Statements:
450 mg/g SULFADIMIDINE
90 mg/g TRIMETHOPRIM
Claims:
For the treatment of infections in horses due to organisms susceptible
to the combination of
sulfadimidine and trimethoprim.
The following bacteria of clinical importance in horses have shown
sensitivity to the 5:1
combination of sulfadimidine and trimethoprim:
Actinobacillus equuli, Escherichia coli, Pasteurella spp.,
Staphylococcus aureus,
Staphylococcus intermedius, Streptococcus equi subsp equi,
Streptococcus
zooepidemicus and Salmonella spp.
Resistance is generally shown by Pseudomonas spp. and Rhodococcus
equi.
Resistance to any antimicrobial can develop.
Net Contents:
250 g
500 g
Directions for Use:
Restraints:
Contraindications:
Precautions:
Side Effects:
Dosage and
Administration:
For oral use only. Each dose should be mixed well with feed or may be
mixed to a paste
and given directly via the mouth.
One level scoop contains 5g sulfadimidine and 1g trimethoprim.
Recommended dose rates
are based on 30mg/kg body weight of combined active ingredients twice
daily.
Administer one scoop per 200kg bodyweight twice daily.
General Directions:
Sulfadimidine is a pyrimidine sulfonamide antimicrobial agent. RLP APPROVED
Trimethoprim is a diaminopyrimidine antimicrobial agent.
The combination of these two agents blocks two sequential steps in
microbial synthesis
of folate. This creates a synergistic action which enhances the
antimicrobial activity of the
combination when compared to the individual components.
This imparts some significant advantages in clinical application:
- the combination is bacteriocidal while each drug alone is
bacteriostatic.
-
t
h
e spectrum of antibacterial activity is broadened.
-
mini
mum inhibitory concentrations are lower than each agent alone.
Sulfadimidine and trimethoprim are readily absorbed following oral
administrat