País: Malàisia
Idioma: anglès
Font: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
AZITHROMYCIN DIHYDRATE
Duopharma Marketing Sdn. Bhd.
AZITHROMYCIN DIHYDRATE
10tablet Tablets; 90tablet Tablets; 30tablet Tablets; 100tablet Tablets; 6tablet Tablets
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
_Consumer Medication Information Leaflet (RiMUP)_ 1 ZYNOMAX 250MG TABLET Azithromycin 250mg WHAT IS IN THIS LEAFLET 1. WHAT ZYNOMAX 250MG TABLET IS USED FOR 2. HOW ZYNOMAX 250MG TABLET WORKS 3. BEFORE YOU USE ZYNOMAX 250MG TABLET 4. HOW TO USE ZYNOMAX 250MG TABLET 5. WHILE YOU ARE USING IT 6. SIDE EFFECTS 7. STORAGE AND DISPOSAL OF ZYNOMAX 250MG TABLET 8. PRODUCT DESCRIPTION 9. MANUFACTURER AND PRODUCT REGISTRATION HOLDER 10. DATE OF REVISION 1. WHAT ZYNOMAX 250MG TABLET IS USED FOR Zynomax 250mg Tablet is used to treat infections caused by certain bacteria and other micro-organisms which include: • Chest, throat, ear or nasal infections (such as bronchitis, pneumonia, tonsillitis, pharyngitis, acute otitis media and sinusitis) • Skin and soft tissue infections (such as an abscess or boil) • Sexually-transmitted diseases caused by organisms called Chlamydia, Haemophilus or Gonorrhoea. 2. HOW ZYNOMAX 250MG TABLET WORKS Zynomax 250mg Tablet is an antibiotic, which belongs to a group of medicines called azalides. The azalides are a sub-class of a group of antibiotics called macrolides. Zynomax 250mg Tablet works by killing or stopping the growth of bacteria causing your infection. Zynomax 250mg Tablet will not work against viral infections such as colds or influenza. Ask your doctor if you have any questions about why Zynomax 250mg Tablet has been prescribed for you. Your doctor may have prescribed it for another reason. Zynomax 250mg Tablet is only available with a doctor's prescription. This medicine is not addictive. 3. BEFORE YOU USE ZYNOMAX 250MG TABLET WHEN YOU MUST NOT TAKE IT Do not take Zynomax 250mg Tablet if you are allergic to: i. azithromycin ii. any other macrolide or ketolide antibiotics (e.g., clarithromycin, erythromycin, roxithromycin, telithromycin) iii. any of the ingredients listed at the end of this leaflet. Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hiv Llegiu el document complet
A. Tablet 250mg Azithromycin 250mg B. Powder for Oral Suspension 200mg/5ml Azithromycin 200mg/5ml CLINICAL PHARMACOLOGY Pharmacodynamic Properties Pharmacotherapeutic group: Macrolides, ATC code J01FA10 . Azithromycin is the first of a subclass of macrolide antibiotics, known as azalides, and is chemically different from erythromycin. Chemically it is derived by insertion of a nitrogen atom into the lactone ring of erythromycin A. The chemical name of azithromycin is 9-deoxy-9a-aza-9a-methyl-9a-homoerythromycin A. The molecular weight is 749.0. Azithromycin binds to the 23S rRNA of the 50S ribosomal subunit. It blocks protein synthesis by inhibiting the transpeptidation/translocation step of protein synthesis and by inhibiting the assembly of the 50S ribosomal subunit. Antibacterial spectrum The susceptibility of bacterial species to azithromycin is shown below. The prevalence of acquired resistance may vary geographically and with time for selected species and local information on resistance is desirable, particularly when treating severe infections. As necessary, expert advice should be sought when the local prevalence of resistance is such that the utility of the agent in at least some types of infections is questionable. In-vitro susceptibility data do not always correlate with clinical results. Organisms that are commonly susceptible to azithromycin include: Aerobic and facultative gram-positive bacteria (erythromycin-susceptible isolates): _S. aureus, Streptococcus agalactiae,* S. _ _pneumoniae,* Streptococcus pyogenes,_* other b-hemolytic streptococci (Groups C, F, G) and viridans streptococci. Macrolide-resistant isolates are encountered relatively frequently among aerobic and facultative gram-positive bacteria, in particular among methicillin-resistant _S. aureus_ (MRSA) and penicillin-resistant _S. pneumoniae _(PRSP). Aerobic and facultative gram-negative bacteria: _ Bordetella pertussis, Haemophilus ducreyi,_*_ Haemophilus influenzae,_* _Haemophilus parainfluenzae,_*_ Legionella pneumophila, Moraxella Llegiu el document complet