Země: Spojené státy
Jazyk: angličtina
Zdroj: NLM (National Library of Medicine)
AMPICILLIN TRIHYDRATE (UNII: HXQ6A1N7R6) (AMPICILLIN - UNII:7C782967RD)
GC Hanford Manufacturing Company
AMPICILLIN TRIHYDRATE
AMPICILLIN 25 g
INTRAMUSCULAR
PRESCRIPTION
Ampicillin for injectable suspension has proved effective in the treatment of many infections previously beyond the spectrum of penicillin therapy. This drug is particularly indicated in the treatment of the following infections caused by susceptible strains of organisms: Dogs and Cats - Respiratory Tract Infections: Upper respiratory infections, tonsillitis and bronchopneumonia due to hemolytic streptococci, Staphylococcus aureus, Escherichia coli, Proteus mirabilis and Pasteurella spp. Urinary Tract Infections due to Proteus mirabilis, Escherichia coli, Staphylococcus spp., hemolytic streptococci and Enterococcus spp. Gastrointestinal Infections due to Enterococcus spp., Staphylococcus spp. and Escherichia coli . Skin, Soft Tissue and Post-Surgical Infections: Abscesses, pustular dermatitis, cellulitis and infections of the anal gland, due to Escherichia coli, Proteus mirabilis , hemolytic streptococci, Staphylococcus spp. and Pasteurella spp. Cattle and Calves Including Non-Ruminating (Veal Cal
Ampicillin for injectable suspension, veterinary is supplied in vials containing 25 grams ampicillin activity as ampicillin trihydrate.
Abbreviated New Animal Drug Application
AMPICILLIN- AMPICILLIN INJECTION, POWDER, FOR SUSPENSION GC HANFORD MANUFACTURING COMPANY ---------- STERILE AMPICILLIN FOR INJECTABLE SUSPENSION, VETERINARY DESCRIPTION: Ampicillin for injectable suspension, veterinary is a broad-spectrum penicillin which has bactericidal activity against a wide range of common gram-positive and gram-negative bacteria. Each 25 g vial contains: 25 g ampicillin activity as ampicillin trihydrate, 90 mg methylparaben (as preservative), 10 mg propylparaben (as preservative), 200 mg lecithin, 500 mg povidone, 200 mg sodium chloride, 600 mg sodium citrate anhydrous. CLINICAL PHARMACOLOGY: The antimicrobial action of ampicillin is bactericidal, and only a small percentage of the antibiotic is serum-bound. Peak serum levels in dogs and cats are reached approximately one-half hour following subcutaneous or intramuscular injection, and in cattle 1 hour to 2 hours following intramuscular injection. _In vitro_ studies have demonstrated sensitivity of the following organisms to ampicillin: gram-positive bacteria - alpha- and beta-hemolytic streptococci, staphylococci (non-penicillinase-producing), _Bacillus_ _anthracis_ and most strains of enterococci and clostridia; gram-negative bacteria - _Proteus mirabilis, E._ _coli_ and many strains of Salmonella and _Pasteurella multocida_. The drug does not resist destruction by penicillinase and, hence, is not effective against strains of staphylococci resistant to penicillin G. Susceptibility tests should be conducted to estimate the _in vitro_ susceptibility of bacterial isolates to ampicillin. INDICATIONS: Ampicillin for injectable suspension has proved effective in the treatment of many infections previously beyond the spectrum of penicillin therapy. This drug is particularly indicated in the treatment of the following infections caused by susceptible strains of organisms: DOGS AND CATS - RESPIRATORY TRACT INFECTIONS: Upper respiratory infections, tonsillitis and bronchopneumonia due to hemolytic streptococci, _Staphylococcus aureus, Escherichia Přečtěte si celý dokument