Země: Kanada
Jazyk: angličtina
Zdroj: Health Canada
CHORIONIC GONADOTROPIN
FRESENIUS KABI CANADA LTD
G03GA01
CHORIONIC GONADOTROPHIN
10000UNIT
POWDER FOR SOLUTION
CHORIONIC GONADOTROPIN 10000UNIT
INTRAMUSCULAR
1/2.5/5/10ML
Prescription
GONADOTROPINS AND ANTIGONADOTROPINS
Active ingredient group (AIG) number: 0106481003; AHFS:
APPROVED
2008-01-10
PRESCRIBING INFORMATION PR CHORIONIC GONADOTROPIN FOR INJECTION, USP 10 000 USP Units Sterile Lyophilized Powder For Intramuscular or Subcutaneous Use GONADOTROPIN FRESENIUS KABI CANADA LTD. 165 Galaxy Blvd, Suite 100 Toronto, ON M9W 0C8 Date of Preparation: August 20, 2019 Submission Control No: 230972 _ _ Chorionic Gonadotropin for Injection, USP – Prescribing Information_ _ _Page 2 of 12 _ PRESCRIBING INFORMATION PR CHORIONIC GONADOTROPIN FOR INJECTION, USP 10 000 USP Units Sterile Lyophilized Powder Gonadotropin DESCRIPTION Chorionic Gonadotropin for Injection, USP (hCG) is extracted from the urine of pregnant women. It is a water-soluble polypeptide hormone produced by the human placenta composed of an alpha and a beta sub-unit. The alpha sub-unit is essentially identical to the alpha sub-units of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), as well as to the alpha sub-unit of human thyroid-stimulating hormone (TSH). The beta sub-units of these hormones differ in amino acid sequence. Chorionic Gonadotropin for Injection, USP (hCG) is biologically standardized and the potency is declared in terms of the USP Reference Standard. ACTIONS The action of hCG is virtually identical to that of pituitary LH, although hCG appears to have a small degree of FSH activity as well. MALE: Chorionic Gonadotropin for Injection, USP is given to males in an effort to stimulate the interstitial cells of the testes (cells of Leydig) to produce androgen. The response to hCG may be considered similar to the effect caused by the interstitial cell stimulating hormone (ICSH) from the anterior lobe of the pituitary. Androgen stimulation in the male leads to the development of secondary sex characteristics and may stimulate testicular descent when no anatomical impediment to descent is present. This descent is usually reversible when hCG is discontinued. Chorionic Gonadotropin for Injection, USP is likely to be of benefit in all conditions directly related to insufficient secretion Přečtěte si celý dokument