Země: Austrálie
Jazyk: angličtina
Zdroj: Department of Health (Therapeutic Goods Administration)
Gliclazide
Apotex Pty Ltd
Medicine Registered
GENRX GLICLAZIDE TABLETS _Contains the active ingredient gliclazide_ CONSUMER MEDICINE INFORMATION _FOR A COPY OF A LARGE PRINT LEAFLET, PH: 1800 195 055_ WHAT IS IN THIS LEAFLET READ THIS LEAFLET CAREFULLY BEFORE TAKING YOUR MEDICINE. This leaflet answers some common questions about gliclazide. It does not contain all the available information. It does not take the place of talking to your doctor, pharmacist or diabetes educator. The information in this leaflet was last updated on the date listed on the last page. More recent information on this medicine may be available. ASK YOUR DOCTOR OR PHARMACIST: • if there is anything you do not understand in this leaflet • if you are worried about taking your medicine, or • to obtain the most up-to-date information. You can also download the most up to date leaflet from www.apotex.com.au. All medicines have risks and benefits. Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. Pharmaceutical companies cannot give you medical advice or an individual diagnosis. Keep this leaflet with your medicine. You may want to read it again. WHAT THIS MEDICINE IS USED FOR The name of your medicine is GenRx Gliclazide. It contains the active ingredient gliclazide. It is used to: • control blood glucose (sugar) in patients with Type II diabetes mellitus. This type of diabetes is also known as non-insulin-dependent diabetes mellitus (NIDDM) or maturity onset diabetes. Gliclazide is used when diet and exercise are not enough to control your blood glucose. Gliclazide can be used alone or together with other medicines for treating diabetes Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason. This medicine is available only with a doctor's prescription. _HOW IT WORKS_ Gliclazide belongs to a group of medicines called the sulfonylureas. Gliclazide lowers high blood glucose by increasing the amount Přečtěte si celý dokument
Product Information – Australia GenRx Gliclazide Tablets Page 1 GENRX GLICLAZIDE TABLETS NAME OF THE MEDICINE Gliclazide Chemical Name: 1-(3-azabicyclo[3.3.0]oct-3-yl)-3-_p_-tolylsulphonylurea. Structural Formula: Molecular Formula: C 15 H 21 N 3 O 3 S Molecular Weight: 323.4 CAS Registry Number: 21187-98-4 DESCRIPTION Gliclazide is a white or almost white powder which is practically insoluble in water. Gliclazide tablets are intended for oral administration. Each tablet contains gliclazide 80 mg. They are round, white, flat-sided tablets with bevelled edge s, engraved “APO” over “80” on one side, cross-scored on the other side. In addition, each tablet contains the following inactive ingredients: croscarmellose sodium, magnesium stearate, colloidal anhydrous silica, lactose, microcrystalline cellulose . PHARMACOLOGY PHARMACODYNAMICS Gliclazide is a sulfonylurea hypoglycaemic agent which restores the diminished first-phase of insulin secretion noted in non-insulin dependant diabetes mellitus. Gliclazide stimulates insulin secretion from functional pancreatic -cells and increases the sensitivity of the -cells to a glucose stimulus (some residual -cell function is therefore necessary). Any long-term hypoglycaemic activity of gliclazide is primarily due to its ability to maintain an effect on insulin secretion, although extrapancreatic effects may also be involved. Extrapancreatic effects demonstrated for gliclazide include improvement in insulin mediated glucose utilisation and potentiation of postreceptor insulin sensitive pat Přečtěte si celý dokument