PROMECTIN- ivermectin injection

Země: Spojené státy

Jazyk: angličtina

Zdroj: NLM (National Library of Medicine)

Aktivní složka:

IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D)

Dostupné s:

Vedco, Inc.

INN (Mezinárodní Name):

IVERMECTIN

Složení:

IVERMECTIN 10 mg in 1 mL

Podání:

SUBCUTANEOUS

Druh předpisu:

OTC

Terapeutické indikace:

ProMectin (ivermectin) Injection has been proved to effectively control infections and to protect cattle from reinfection with Dictyocaulus viviparus and Oesophagostomum radiatum for 28 days after treatment; Ostertagia ostertagi, Trichostrongylus axei and Cooperia punctata for 21 days after treatment; Haemonchus placei and Cooperia oncophora for 14 days after treatment. Swine :  ProMectin (ivermectin) Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, lice and mange mites in swine:

Přehled produktů:

50 mL, 200 mL, 500 mL

Stav Autorizace:

Abbreviated New Animal Drug Application

Charakteristika produktu

PROMECTIN - IVERMECTIN INJECTION
VEDCO, INC.
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PROMECTIN INJECTION (IVERMECTIN)
FOR CATTLE AND SWINE
1% STERILE SOLUTION
A PARASITICIDE FOR THE TREATMENT AND CONTROL OF INTERNAL AND EXTERNAL
PARASITES OF CATTLE AND
SWINE
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT,
AND CONTROL OF PARASITISM.
INTRODUCTION
Ivermectin is an injectable parasiticide for cattle and swine. One
low-volume dose effectively treats and
controls the following internal and external parasites that may impair
the health of cattle and swine:
gastrointestinal roundworms (including inhibited _Ostertagia
ostertagi_ in cattle), lungworms, grubs,
sucking lice, and mange mites of cattle; and gastrointestinal
roundworms, lungworms, lice, and mange
mites in swine.
PRODUCT DESCRIPTION
Ivermectin is derived from the avermectins, a family of potent,
broad-spectrum antiparasitic agents
isolated from fermentation of_ Streptomyces avermitilis._
ProMectin (ivermectin) Injection is a clear, ready-to-use, sterile
solution containing 1% ivermectin,
40% glycerol formal, and propylene glycol, q.s. ad 100%. ProMectin
(ivermectin) Injection is
formulated to deliver the recommended dose level of 200 mcg
ivermectin/kilogram of body weight in
cattle when given subcutaneously at the rate of 1 mL/110 lb (50 kg).
In Swine, ProMectin (ivermectin)
Injection is formulated to deliver the recommended dose level of 300
mcg ivermectin/kilogram body
weight when given subcutaneously in the neck at the rate of 1 mL/75
lbs (33 kg).
MODE OF ACTION
Ivermectin is a member of the macrocyclic lactone class of
endectocides which have a unique mode of
action. Compounds of the class bind selectively and with high affinity
to glutamate-gated chloride ion
channels which occur in invertebrate nerve and muscle cells. This
leads to an increase in the
permeability of the cell membrane to chloride ions with
hyperpolarization of the nerve or muscle cell,
resulting in paralysis and death of the parasite. Compounds of this
class may also interact with other
ligand-gat