Land: USA
Sprog: engelsk
Kilde: NLM (National Library of Medicine)
ATROPINE SULFATE (UNII: 03J5ZE7KA5) (ATROPINE - UNII:7C0697DR9I)
Cardinal Health
INTRAVENOUS
PRESCRIPTION DRUG
Atropine Sulfate Injection, USP is indicated (1) as an antisialogogue for preanesthetic medication to prevent or reduce secretions of the respiratory tract, (2) to restore cardiac rate and arterial pressure during anesthesia when vagal stimulation produced by intra-abdominal surgical traction causes a sudden decrease in pulse rate and cardiac action, (3) to lessen the degree of atrioventricular (A-V) heart block when increased vagal tone is a major factor in the conduction defect as in some cases due to digitalis, (4) to overcome severe bradycardia and syncope due to a hyperactive carotid sinus reflex, (5) as an antidote (with external cardiac massage) for cardiovascular collapse from the injudicious use of a choline ester (cholinergic) drug, (6) in the treatment of anticholinesterase poisoning from organophosphorus insecticides, and (7) as an antidote for the “rapid” type of mushroom poisoning due to the presence of the alkaloid, muscarine, in certain species of fungus such as Amanita muscaria . Atropine ge
Atropine Sulfate Injection, USP is supplied in single-dose containers as follows: List No. Needle Size Conc. Total Content (Atropine) LifeShield ® Abboject Unit of Use Syringe with male luer lock adapter and protected needle 4910 20-G 5 mL 0.1 mg/mL (Adult) 0.5 mg 4911 20-G 10 mL 0.1 mg/mL (Adult) 1 mg Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Revised: February, 2007 Printed in USA EN-1435 Hospira, Inc., Lake Forest, IL 60045 USA Cardinal Health Zanesville, OH 43701 IA60031111
unapproved drug other
ATROPINE SULFATE- ATROPINE SULFATE INJECTION, SOLUTION CARDINAL HEALTH _Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been_ _approved by FDA. For further information about unapproved drugs, click here._ ---------- ATROPINE SULFATE Injection, USP 0.1 MG/ML LIFESHIELD ABBOJECT UNIT OF USE SYRINGE R only DESCRIPTION Atropine Sulfate Injection, USP is a sterile, nonpyrogenic isotonic solution of atropine sulfate monohydrate in water for injection with sodium chloride sufficient to render the solution isotonic. It is administered parenterally by subcutaneous, intramuscular or intravenous injection. Each milliliter (mL) contains atropine sulfate, monohydrate 0.1 mg (adult strength) and sodium chloride, 9 mg. May contain sodium hydroxide and/or sulfuric acid for pH adjustment 0.308 mOsmol/mL (calc.). pH 4.2 (3.0 to 6.5). The solution contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended for use only as a single-dose injection. When smaller doses are required the unused portion should be discarded. Atropine Sulfate Injection is a parenteral anticholinergic agent and muscarinic antagonist. Atropine Sulfate, USP is chemically designated 1α H, 5α H-Tropan-3-α ol (±)-tropate (ester), sulfate (2:1) (salt) monohydrate, (C H NO ) • H SO • H O, colorless crystals or white crystalline powder very soluble in water. It has the following structural formula: Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and 1- hyocyamine, whose activity is due almost entirely to the levo isomer of the drug. ® x 17 23 3 2 2 4 2 Sodium Chloride, USP is chemically designated NaCl, a white crystalline powder freely soluble in water. CLINICAL PHARMACOLOGY Atropine is commonly classified as an anticholinergic or antiparasympathetic (parasympatholytic) drug. More precisely, however, it is termed an antimuscarinic agent since it antagonizes the muscarine-like actions of acetyl-choline and other cho Læs hele dokumentet