Land: Australien
Sprache: Englisch
Quelle: Department of Health (Therapeutic Goods Administration)
acetylcysteine, Quantity: 800 mg
Omegapharm
acetylcysteine
Solution
Excipient Ingredients: hydrochloric acid; water for injections; disodium edetate; sodium hydroxide
Intratracheal, Nasal
1 x 4 mL vials, 10 x 4 mL vials
(S4) Prescription Only Medicine
Adjuvant therapy for patients with abnormal, viscid or inspissated mucous secretions in such conditions as: - chronic bronchopulmonary disease (chronic emphysema, emphysema with bronchitis, chronic asthmatic bronchitis, tuberculosis, bronchiectasis and primary amyloidosis of the lung); - acute bronchopulmonary disease (pneumonia, bronchitis, tracheobronchitis); - pulmonary complications of cystic fibrosis; - pulmonary complications associated with surgery; - post-traumatic chest conditions; - atelectasis due to mucus obstruction; - tracheostomy care; - anaesthesia. Acetylcysteine may also be used as an adjunct to diagnostic bronchial studies (bronchograms, bronchospirometry and bronchial wedge catheterisation).
Visual Identification: Clear colourless solution; Container Type: Vial; Container Material: Glass; Container Life Time: 18 Months; Container Temperature: Store below 25 degrees Celsius
Registered
2011-02-28
Omegapharm Acetylcysteine Solution for Inhalation 1/6 v1.1 March 2011 OMEGAPHARM ACETYLCYSTEINE SOLUTION FOR INHALATION _(as-et-il-cist-ene)_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Omegapharm Acetylcysteine Solution for Inhalation. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of your treatment using Omegapharm Acetylcysteine Solution for Inhalation against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT OMEGAPHARM ACETYLCYSTEINE SOLUTION FOR INHALATION IS USED FOR The name of your medicine is Omegapharm Acetylcysteine Solution for Inhalation. It contains the active ingredient called acetylcysteine. Omegapharm Acetylcysteine Solution for Inhalation reduces the stickiness of fluid in your airways and lungs, making it more liquid. Omegapharm Acetylcysteine Solution for Inhalation is used in patients with abnormal, sticky or thick mucous secretions in conditions such as: • ongoing lung disease such as pneumonia, bronchitis, emphysema, tuberculosis and other conditions that affect your breathing • short term lung disease such as pneumonia or bronchitis • lung problems of cystic fibrosis • lung problems occurring after an accident or after surgery • other lung problems associated with having mucus in your airway Omegapharm Acetylcysteine Solution for Inhalation may also be used: • when you are having tests carried out on your lungs • as part of tracheostomy care • when you are receiving an anaesthetic Your doctor may have prescribed Omegapharm Acetylcysteine Solution for Inhalation for another reason. Ask your doctor if you have any questions about why Omegapharm Acetylcysteine Solution for Inhalation has been prescribed for you. There is no Lesen Sie das vollständige Dokument
Omegapharm Acetylcysteine Solution 200 mg/mL 1/5 v1.0 Feb 2011 PRODUCT INFORMATION OMEGAPHARM ACETYLCYSTEINE SOLUTION FOR INHALATION NAME OF THE MEDICINE Acetylcysteine Acetylcysteine is a white, crystalline powder with a slight acetic odour. It is soluble in water and alcohol and practically insoluble in chloroform, dichloromethane and ether. Acetylcysteine is the _N_-acetyl derivative of the naturally occurring amino acid, L-cysteine. The chemical name is _N_-acetyl-mercapto-alanine. Chemical Name: (2_R_)-2-acetamino-3-sulfanylpropanoic acid Molecular Formula: C 5 H 9 NO 3 S. Molecular Weight: 163.2 CAS Registry Number: 616-91-1. DESCRIPTION Acetylcysteine solution is a sterile solution for inhalation (mucolytic agent) containing the active ingredient acetylcysteine 20%w/v (200 mg/mL) and the inactive ingredients disodium edetate, sodium hydroxide and water for injections. The product may also contain hydrochloric acid for pH adjustment. The pH of the product is maintained in the range of 6.0 – 7.5. The solution is presented in clear glass vials containing 4 mL or 10 mL of solution. This product is not for injection. PHARMACOLOGY Acetylcysteine, the _N_-acetyl derivative of the naturally occurring amino acid L-cysteine, is neither an enzyme nor a detergent. The viscosity of pulmonary mucous secretions depends on the concentrations of mucoprotein and to a lesser extent deoxyribonucleic acid (DNA). The latter increases with increasing purulence owing to cellular debris. The mucolytic action of acetylcysteine is related to the sulfhydryl group in the molecule. This group probably 'opens' disulfide linkages in mucus, thereby lowering the viscosity. The mucolytic activity of acetylcysteine is unaltered by the presence of DNA, and increases with increasing pH. Significant mucolysis occurs between pH 7 and 9. PHARMACOKINETICS Acetylcysteine is the acetyl derivative of the normally occurring amino acid, L-cysteine. Any absorbed acetylcysteine probably undergoes deacetylation and the remaining cysteine follows the nor Lesen Sie das vollständige Dokument