ADVANTAGE MULTI FOR DOGS- imidacloprid moxidectin solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

IMIDACLOPRID (UNII: 3BN7M937V8) (IMIDACLOPRID - UNII:3BN7M937V8), MOXIDECTIN (UNII: NGU5H31YO9) (MOXIDECTIN - UNII:NGU5H31YO9)

Available from:

Bayer HealthCare LLC Animal Health Division

INN (International Name):

IMIDACLOPRID

Composition:

IMIDACLOPRID 100 mg in 1 mL

Administration route:

TOPICAL

Prescription type:

PRESCRIPTION

Therapeutic indications:

Advantage Multi for Dogs is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and the treatment of Dirofilaria immitis circulating microfilariae in heartworm-positive dogs. Advantage Multi for Dogs kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis ). Advantage Multi for Dogs is indicated for the treatment and control of sarcoptic mange caused by Sarcoptes scabiei var. canis. Advantage Multi for Dogs is also indicated for the treatment and control of the following intestinal parasites: Intestinal Parasite Intestinal Stage Adult Immature Adult Fourth Stage Larvae Hookworm Species Ancylostoma caninum X X X Uncinaria stenocephala X X X Roundworm Species Toxocara canis X X Toxascaris leonina X Whipworm Trichuris vulpis X Do not administer this product orally. (See WARNINGS.) Do not use this product (containing 2.5% moxidectin) on cats.

Product summary:

Applications Per Package: 6 x 0.4 mL tubes 6 x 1.0 mL tubes 6 x 2.5 mL tubes 6 x 4.0 mL tubes 6 x 5.0 mL tubes

Authorization status:

New Animal Drug Application

Summary of Product characteristics

ADVANTAGE MULTI FOR DOGS- IMIDACLOPRID MOXIDECTIN SOLUTION
BAYER HEALTHCARE LLC ANIMAL HEALTH DIVISION
----------
ADVANTAGE MULTI
FOR DOGS
(IMIDACLOPRID + MOXIDECTIN)
TOPICAL SOLUTION
ONCE-A-MONTH TOPICAL SOLUTION FOR THE PREVENTION OF HEARTWORM DISEASE,
THE TREATMENT OF
CIRCULATING MICROFILARIAE, KILLS ADULT FLEAS, IS INDICATED FOR THE
TREATMENT OF FLEA INFESTATIONS, THE
TREATMENT AND CONTROL OF SARCOPTIC MANGE, AS WELL AS THE TREATMENT AND
CONTROL OF INTESTINAL
PARASITE INFECTIONS IN DOGS AND PUPPIES THAT ARE AT LEAST 7 WEEKS OF
AGE AND THAT WEIGH AT LEAST 3
LBS .
WARNING
•
•
•
(SEE CONTRAINDICATIONS, WARNINGS, HUMAN WARNINGS, AND ADVERSE
REACTIONS, FOR MORE
INFORMATION)
CAUTION:
Federal (U.S.A.) Law restricts this drug to use by or on the order of
a licensed veterinarian.
DESCRIPTION:
_Advantage Multi_® _for Dogs _(10 % imidacloprid + 2.5 % moxidectin)
is a colorless to yellow ready-to-
use solution packaged in single dose applicator tubes for topical
treatment of dogs. The formulation and
dosage schedule are designed to provide a minimum of 4.5 mg/lb (10
mg/kg) imidacloprid and 1.1 mg/lb
(2.5 mg/kg) moxidectin based on body weight.
Imidacloprid is a chloronicotinyl nitroguanidine insecticide. The
chemical name for imidacloprid is 1-
[(6-Chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine. Moxidectin
is a semisynthetic
macrocyclic lactone endectocide derived from the actinomycete
_Streptomycetes cyaneogriseus_
_noncyanogenus_. The chemical name for moxidectin is [6R, 23E,
25S(E)]-5-O- Demethyl-28-deoxy-25-
(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino) milbemycin B.
INDICATIONS:
_Advantage Multi for Dogs _is indicated for the prevention of
heartworm disease caused by _Dirofilaria_
_immitis _and the treatment of _Dirofilaria immitis _circulating
microfilariae in heartworm-positive dogs.
_Advantage Multi for Dogs _kills adult fleas and is indicated for the
treatment of flea infestations
(_Ctenocephalides felis_). _Advantage Multi for Dogs _is indicated for
the treatment and control of sarcoptic