Aspen Adenosine

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Adenosine

Available from:

Aspen Pharmacare Australia Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

ASPEN ADENOSINE

_adenosine 6 mg/2 mL injection_
CONSUMER MEDICINE INFORMATION (CMI)

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Aspen Adenosine. It
does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using Aspen
Adenosine against the benefits they
expect it will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
BEING TREATED WITH THIS MEDICINE,
ASK YOUR DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET EVEN AFTER YOUR
TREATMENT IS FINISHED.
You may want to read it again.
WHAT ASPEN
ADENOSINE IS USED FOR
Aspen Adenosine is used to treat a
condition called paroxysmal
supraventricular tachycardia
(including a condition called Wolff-
Parkinson-White syndrome). This is
when the heart beats too rapidly. If
left untreated, this condition can be
life threatening.
Aspen Adenosine can also be used as
an aid to doctors to understand how
your heart is working.
It works by slowing down the
electrical impulses that control heart
rhythm. This allows the heart rhythm
to return to normal.
Aspen Adenosine is only given in
hospitals. It is given to you as an
injection. The effect of this medicine
only lasts for a couple of minutes.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY ASPEN
ADENOSINE HAS BEEN PRESCRIBED FOR
YOU.
Your doctor may have prescribed it
for another use.
This medicine is available only with
a doctor's prescription.
There is no evidence that it is
addictive.
BEFORE YOU ARE GIVEN IT
_WHEN YOU MUST NOT BE GIVEN_
_IT_
YOU MUST NOT BE GIVEN ASPEN
ADENOSINE IF YOU HAVE EVER HAD AN
ALLERGIC REACTION TO:
•
any medicine containing
adenosine, the active ingredient
•
any of the ingredients listed at the
end of this leaflet.
Some of the symptoms of an allergic
reaction may include shortness of
breath, wheezing or difficulty
breathing; swelling of the face, lips,
tongue or other parts of the body;
rash, itching or hives on the skin.
YOU MUST NOT

Summary of Product characteristics

PRODUCT INFORMATION 

ASPEN ADENOSINE INJECTION 
(6 MG/2 ML) 

NAME OF THE MEDICINE 

Non-Proprietary Name:  Adenosine 
Chemical Name: 
9-β-D-ribofuranosyl-9H-purin-6-amine 
Molecular formula: 
C
10
H
13
N
5
O
4
Chemical Structure: 

CAS Number: 58-61-7 
MW: 267.2 

DESCRIPTION 

Adenosine is a white, crystalline powder slightly soluble in water,
soluble in hot water, 
practically insoluble in alcohol and in methylene chloride. 

Aspen Adenosine is a sterile solution for intravenous injection (rapid
bolus), available in clear 
glass vials and pre-filled syringes.    Each vial or
pre-syringe contains adenosine and sodium 
chloride in water for injections, pH between 4.5 and 7.5. 

PHARMACOLOGY 

Aspen Adenosine administered by rapid intravenous injection depresses
conduction through 
the atrioventricular (AV) node.     
This action can interrupt re-entry circuits involving the AV node and
restore normal sinus 
rhythm in patients with paroxysmal supraventricular tachycardias and
paroxysmal 
ASPEN ADENOSINE
 – Marketed Product Information                                                                Page 1 of 10 

supraventricular tachycardias associated with Wolff-Parkinson-White
Syndrome.    Once the 
circuit has been interrupted, the tachycardia stops and normal sinus
rhythm is re-established.   

By transiently slowing AV conduction, atrial activity is easier to
evaluate from ECG 
recordings and therefore Aspen Adenosine can aid the diagnosis of
broad or narrow QRS 
complex tachycardias.   

Aspen Adenosine may be useful during electrophysiological studies to
determine the site of 
AV block or to determine, in some cases of pre-excitation, whether
conduction is occurring 
by an accessory pathway or via the AV node.   

HAEMODYNAMICS 

The usual intravenous bolus dose of 3 mg or 6 mg Aspen Adenosine
usually has no systemic 
haemodynami