Axcel Atenolol-50mg Tablet

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

ATENOLOL

Available from:

KOTRA PHARMA (M) SDN. BHD.

INN (International Name):

ATENOLOL

Units in package:

28tablet Tablets

Manufactured by:

KOTRA PHARMA (M) SDN. BHD.

Patient Information leaflet

AXCEL ATENOLOL TABLETS
_Atenolol (50mg & 100mg) _
_ _
_ _
1
_Consumer Medication Information Leaflet (RiMUP) _
WHAT IS IN THIS LEAFLET
1.
What Axcel Atenolol Tablets Is
Used For.
2.
How
Axcel
Atenolol
Tablets
Works.
3.
Before You Use Axcel Atenolol
Tablets.
4.
How
to
Take
Axcel
Atenolol
Tablets.
5.
While You Are Using It.
6.
Side Effects.
7.
Storage and Disposal of Axcel
Atenolol Tablets.
8.
Product Description.
9.
Manufacturer
and
Product
Registration Holder.
WHAT AXCEL
ATENOLOL TABLETS IS USED
FOR
Axcel Atenolol Tablets is used for

Control of high blood pressure

Management of chest pain

Control of irregular heartbeat

Treatment of heart attack. Early
and late intervention.
HOW AXCEL
ATENOLOL TABLETS WORKS
Atenolol is a beta-blocker, where the
mode of action in the treatment of
high blood pressure is unclear. It is
probably
the
action
of
atenolol
in
reducing heart rate and contractility
which
makes
it
effective
in
eliminating or reducing the symptoms
of
patients
with
chest
pain.
Early
intervention
with
atenolol
in
heart
attack helps to reduce the size of area
of dying heart tissues.
BEFORE YOU USE AXCEL
ATENOLOL TABLETS
WHEN YOU MUST NOT USE IT
Do not take Axcel Atenolol Tablets if:

If
you
are
allergic
or
hypersensitive to any component
of this medication.

If you have very slow heartbeat;
your
heart
unable
to
pump
as
much blood as the body needs;
low
blood
pressure;
severe
peripheral
arterial
circulatory
disturbances (in which narrowed
arteries
reduced
blood
flow
to
your
limbs);
second
or
third
degree
heart
block;
sick
sinus
syndrome
(a
collection
of
abnormal
heart
rhythm);
untreated
phaeochromocytoma
(rare
tumor
of
adrenal
gland
tissue);
uncontrolled
heart
failure.
BEFORE YOU START TO USE IT
Tell your doctor if:

If
you
are
pregnant
or
breast
feeding.

If you have impaired respiratory
function.

If you have kidney impairment.
TAKING OTHER MEDICINES
You should tell your doctor if you are
taking
any
medicines
as
it
may
interact
with
your
Axcel
Atenolol
Tablets.
HOW TO USE AXCEL
ATE

Summary of Product characteristics

action of atenolol in reducing cardiac rate and contractility which
makes it
effective in eliminating or reducing the symptoms of patients with
angina. It
is unlikely that any additional ancillary properties possessed by S
(-)
atenolol, in comparison with the racemic mixture, will give rise to
different
therapeutic effects. Atenolol is effective and well-tolerated in most
ethnic
populations although the response may be less in black patients.
Atenolol is
effective for at least 24 hours after a single oral dose. The drug
facilitates
compliance by its acceptability to patients and simplicity of dosing.
The
narrow dose range and early patient response ensure that the effect of
the
drug in individual patients is quickly demonstrated. Atenolol is
compatible
with diuretics, other hypotensive agents and antianginal agents (see
_Drug _
_Interaction_). Since it acts preferentially on beta-receptors in the
heart,
atenolol may, with care, be used successfully in the treatment of
patients
with respiratory disease, who cannot tolerate non-selective
beta-blockers.
Early intervention with atenolol in acute myocardial infarction
reduces
infarct sizes and decreases morbidity and mortality. Fewer patients
with a
threatened
infarction
progress
to
frank
infarction;
the
incidence
of
ventricular arrhythmias is decreased and marked pain relief may result
in
reduced need of opiate analgesics. Early mortality is decreased.
Atenolol is
an additional treatment to standard coronary care.
_Pharmacokinetics: _
Absorption of atenolol following oral dosing is consistent but
incomplete
(approximately 40-50%) with peak plasma concentrations occurring 2-4
hours after dosing. The atenolol blood levels are consistent and
subject to
little variability. There is no significant hepatic metabolism of
atenolol and
more than 90% of the absorbed reaches the systemic circulation
unaltered.
The plasma half-life is about 6 hours but this may arise in severe
renal
impairment since the kidney is the major route of elimination.
Atenolol
penetrates tissue poorly