Axiron

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Testosterone

Available from:

Eli Lilly Australia Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

AXIRON
®

_testosterone_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about AXIRON. It does not
contain all the available information.
It does not take the place of talking to
your doctor or pharmacist.
For detailed instructions on the use of
AXIRON, please read the Applicator
Instructions for Use leaflet located
inside the pack, prior to using
AXIRON.
The information in this leaflet was
last updated on the date shown on the
final page. More recent information
on this medicine may be available.
Make sure you speak to your
pharmacist, nurse or doctor to obtain
the most up to date information on
this medicine. You can also
download the most up to date leaflet
from www.lilly.com.au. The updated
leaflet may contain important
information about AXIRON and its
use that you should be aware of.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using AXIRON
against the benefits they expect it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
USING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
YOU MAY NEED TO READ IT AGAIN.
WHAT AXIRON IS USED
FOR
AXIRON is used to replace them
body's natural hormone testosterone
when not enough is made by the
body.
Testosterone is a natural male
hormone, known as an androgen,
which controls normal sexual
development in men.
Testosterone is essential for the
development and maintenance of the
male reproductive organs as well as
other male characteristics, such as
deep voice, increased muscle
strength, hair growth etc.
AXIRON is a testosterone containing
solution that is applied daily to the
armpit(s). The testosterone passes
through the skin and into the
bloodstream.
The testosterone in AXIRON is
identical to the naturally occurring
testosterone present in the body.
A doctor's prescription is required to
obtain this medicine.
This medicine is not addictive. This
medicine is not expected to affect
your ability to drive a car or operate
machinery.
Ask your doc

Summary of Product characteristics

 
axiron-pi-v1-15may12 

Page 1 of 13 
AXIRON
®

(testosterone) 2% w/v transdermal solution 

NAME OF THE MEDICINE 

AXIRON
®
 (testosterone). 

Testosterone AAN is a fragrance
free white to practically white crystalline powder chemically 
described as 17-beta hydroxyandrost-4-en-3-one. Testosterone has the empirical
formula C
19
H
28
O
2

representing a molecular weight of 288.43.
The CAS number for testosterone is 58-22-0. 

Pharmacotherapeutic group: Androgens, ATC code: G03BA03 

Testosterone has the following structural formula: 

DESCRIPTION 

AXIRON (testosterone)  transdermal solution is a
clear, colourless, fragrance free, single phase 
solution containing 30 mg of testosterone in 1.5
mL of AXIRON solution for transdermal 
administration through
the underarm. The active pharmacologic ingredient in AXIRON is 
testosterone. The inactive ingredients are ethanol, isopropyl alcohol, octyl
salicylate, and povidone. 

PHARMACOLOGY 

Testosterone and dihydrotestosterone (DHT), endogenous androgens,
are responsible for the 
normal growth and development of the male sex organs and
for the maintenance of secondary sex 
characteristics. These effects include the growth and maturation
of the prostate, seminal vesicles, 
penis and scrotum; the development of male hair distribution on
the face, chest, axillae and pubis; 
laryngeal enlargement, vocal chord thickening, alterations in
body musculature and fat distribution. 

Insufficient secretion of testosterone due to testicular failure,
pituitary pathology or gonadotropin 
or luteinising hormone-releasing hormone deficiency results in
male hypogonadism and low serum 
testosterone concentration.
Symptoms associated with low testosterone include
decreased sexual 
desire with or without erectile dysfunction, fatigue,
loss of muscle mass, mood depression and�