Country: United States
Language: English
Source: NLM (National Library of Medicine)
CEFTIOFUR SODIUM (UNII: NHI34IS56E) (CEFTIOFUR - UNII:83JL932I1C)
Aspen Veterinary Resources Ltd.
INTRAMUSCULAR
PRESCRIPTION
Cattle Ceftiofur Sodium Sterile Powder is indicated for treatment of bovine respiratory disease (shipping fever, pneumonia) associated with Mannheimia haemolytica , Pasteurella multocida and Histophilus somni . Ceftiofur Sodium Sterile Powder is also indicated for treatment of acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus . Swine Ceftiofur Sodium Sterile Powder is indicated for treatment/control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus (Haemophilus) pleuropneumoniae , Pasteurella multocida , Salmonella choleraesuis and Streptococcus suis . Sheep Ceftiofur Sodium Sterile Powder is indicated for treatment of sheep respiratory disease (sheep pneumonia) associated with Mannheimia haemolytica and Pasteurella multocida . Goat Ceftiofur Sodium Sterile Powder is indicated for treatment of caprine respiratory disease (goat pneumonia) associated with Mannheimia ha
Ceftiofur Sodium Sterile Powder is available in the following package sizes: 1 gram vial 4 gram vial 1. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals; Approved Standard - Second Edition. NCCLS document M31-A2. CLSI, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898, 2002. ANADA 200-420, Approved by FDA Mfd for: Aspen Veterinary Resources Ltd. By: Cephazone Pharma LLC Liberty, MO 64068 Pomona, CA 91767
Abbreviated New Animal Drug Application
CEFTIFLEX- CEFTIOFUR SODIUM INJECTION, POWDER, FOR SOLUTION ASPEN VETERINARY RESOURCES LTD. ---------- CEFTIOFUR SODIUM STERILE POWDER FOR INTRAMUSCULAR AND SUBCUTANEOUS INJECTION IN CATTLE ONLY. FOR INTRAMUSCULAR INJECTION IN SWINE, SHEEP, GOATS, AND HORSES. FOR SUBCUTANEOUS INJECTION ONLY IN DOGS, DAY-OLD CHICKENS AND DAY-OLD TURKEY POULTS. THIS PRODUCT MAY BE USED IN LACTATING DAIRY CATTLE, SHEEP, AND GOATS. CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION Ceftiofur Sodium Sterile Powder contains the sodium salt of ceftiofur which is a broad spectrum cephalosporin antibiotic active against gram-positive and gram-negative bacteria including β-lactamase- producing strains. Like other cephalosporins, ceftiofur is bactericidal _in vitro_, resulting from inhibition of cell wall synthesis. Each mL of the reconstituted drug contains ceftiofur sodium equivalent to 50 mg ceftiofur. The pH was adjusted with sodium hydroxide and monobasic potassium phosphate. Chemical structure of Ceftiofur Sodium Chemical Name of Ceftiofur Sodium 5-Thia-1-azabicyclo [4.2.0] oct-2-ene-carboxylic acid, 7-[[(2-amino-4-thiazoly)(methoxyimino)- acetyl]amino]-3-[[(2-furanylcarbonyl)thio] methyl]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]- RECONSTITUTION OF THE STERILE POWDER Ceftiofur Sodium Sterile Powder should be reconstituted as follows: 1 GRAM VIAL- Reconstitute with 20 mL Sterile Water for Injection. Each mL of the resulting solution contains ceftiofur sodium equivalent to 50 mg ceftiofur. 4 GRAM VIAL- Reconstitute with 80 mL Sterile Water for Injection. Each mL of the resulting solution contains ceftiofur sodium equivalent to 50 mg ceftiofur. Shake thoroughly prior to use. INDICATIONS CATTLE Ceftiofur Sodium Sterile Powder is indicated for treatment of bovine respiratory disease (shipping fever, pneumonia) associated with _Mannheimia haemolytica_, _Pasteurella multocida _and _Histophilus somni_. Ceftiofur Sodium Sterile Powder is also indicated for treatment of acute bovi Read the complete document