DIPROSPAN INJECTION

Country: Singapore

Language: English

Source: HSA (Health Sciences Authority)

Active ingredient:

BETAMETHASONE DIPROPIONATE EQV BETAMETHASONE ALCOHOL; BETAMETHASONE DISODIUM PHOSPHATE EQV BETAMETHASONE ALCOHOL

Available from:

MSD PHARMA (SINGAPORE) PTE. LTD.

ATC code:

H02AB01

Dosage:

5 mg/ml

Pharmaceutical form:

INJECTION

Composition:

BETAMETHASONE DIPROPIONATE EQV BETAMETHASONE ALCOHOL 5 mg/ml; BETAMETHASONE DISODIUM PHOSPHATE EQV BETAMETHASONE ALCOHOL 2 mg/ml

Administration route:

INTRA-ARTICULAR, INTRABURSAL, INTRALESIONAL, PERIARTICULAR

Prescription type:

Prescription Only

Manufactured by:

SCHERING-PLOUGH LABO NV

Authorization status:

ACTIVE

Authorization date:

1990-06-22

Patient Information leaflet

 
1 
DIPROSPAN
®

Injection 

BRAND OF STERILE BETAMETHASONE DIPROPIONATE AND BETAMETHASONE 
DISODIUM PHOSPHATE, N.F. 

This insert contains basic prescribing information only.  

For more comprehensive information, a Professional  

Brochure is available to physicians upon request. 

MSD 

As this preparation contains benzyl alcohol, its use should be
avoided in children under two 
years of age.  Not to be used in neonates. 

FOR INTRAMUSCULAR, INTRA-ARTICULAR, PERIARTICULAR, INTRABURSAL, 
INTRADERMAL, INTRALESIONAL AND SOFT TISSUE INJECTION 

DESCRIPTION:  DIPROSPAN Suspension is a sterile
aqueous injectable suspension of 
betamethasone dipropionate and betamethasone disodium phosphate. 
Each ml of 
DIPROSPAN Suspension contains betamethasone dipropionate
equivalent to 5 mg 
betamethasone and  betamethasone disodium phosphate equivalent to 2
mg betamethasone 
in a sterile buffered and preserved vehicle.  Inactive ingredients: 
Dibasic anhydrous sodium 
phosphate, sodium chloride, disodium edetate, polysorbate
80, benzyl alcohol, 
methylparaben, propylparaben, sodium carboxymethylcellulose, polyethylene
glycol 3350 and 
water for injection.  Preservatives: benzyl alcohol 9.0
mg/ml, methylparaben 1.3 mg/ml and 
propylparaben 0.2 mg/ml. 

ACTIONS:  DIPROSPAN Suspension is a combination of soluble and
very slightly soluble 
betamethasone
esters that provides potent anti-inflammatory, antirheumatic and
antiallergic 
effects in the treatment of corticosteroid-responsive disorders. 
Prompt therapeutic activity is 
achieved by the soluble ester, betamethasone
disodium phosphate, which is absorbed quickly 
after injection.  Sustained activity is provided by betamethasone
dipropionate, which is only 
slightly soluble and becomes a
repository for slow absorption, thereby controlling symptoms 
over a prolonged period. The small c

Summary of Product characteristics

S-CCDS-MK1460B-SUi-082017a
Diprospan® Injection
BRAND OF STERILE BETAMETHASONE DIPROPIONATE AND BETAMETHASONE DISODIUM
PHOSPHATE, N.F.
As this preparation contains benzyl alcohol, its use should be avoided
in children under two years of
age. Not to be used in neonates.
FOR
INTRAMUSCULAR,
INTRA-ARTICULAR,
PERIARTICULAR,
INTRABURSAL,
INTRADERMAL, INTRALESIONAL AND SOFT TISSUE INJECTION
DESCRIPTION:
DIPROSPAN
Suspension
is
a
sterile
aqueous
injectable
suspension
of
betamethasone dipropionate and betamethasone disodium phosphate. Each
ml of DIPROSPAN
Suspension
contains
betamethasone
dipropionate
equivalent
to
5 mg
betamethasone
and
betamethasone disodium phosphate equivalent to 2 mg betamethasone in a
sterile buffered and
preserved vehicle. Inactive ingredients:
Disodium hydrogen phosphate dihydrate, sodium chloride,
disodium
edetate,
polysorbate
80,
benzyl
alcohol,
methylparaben,
propylparaben,
sodium
carboxymethylcellulose,
polyethylene
glycol
3350,
hydrochloric
acid
and
water
for
injection.
Preservatives: benzyl alcohol 9.0 mg/ml, methylparaben 1.3 mg/ml and
propylparaben 0.2 mg/ml.
ACTIONS:
DIPROSPAN
Suspension
is
a
combination
of
soluble
and
very
slightly
soluble
betamethasone esters that provides potent anti-inflammatory,
antirheumatic and antiallergic effects
in the treatment of corticosteroid-responsive disorders. Prompt
therapeutic activity is achieved by
the soluble ester, betamethasone disodium phosphate, which is absorbed
quickly after injection.
Sustained activity is provided by betamethasone dipropionate, which is
only slightly soluble and
becomes a repository for slow absorption, thereby controlling symptoms
over a prolonged period.
The small crystal size of betamethasone dipropionate permits the use
of a fine-gauge needle (up to
26 gauge) for intradermal and intralesional administration.
Glucocorticosteroids, such as betamethasone, cause profound and varied
metabolic effects and
modify the body’
s immune response to diverse stimuli.
Betamethasone has high glucocorticosteroid activity and slight
mi