EQUIOXX- firocoxib tablet, chewable

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

firocoxib (UNII: Y6V2W4S4WT) (firocoxib - UNII:Y6V2W4S4WT)

Available from:

Merial, Inc.

INN (International Name):

firocoxib

Composition:

firocoxib 57 mg

Administration route:

ORAL

Prescription type:

PRESCRIPTION

Therapeutic indications:

EQUIOXX Tablets are administered once daily for up to 14 days for the control of pain and inflammation associated with osteoarthritis in horses. Horses with a hypersensitivity to firocoxib should not receive EQUIOXX® Tablets.

Product summary:

EQUIOXX is available as round, beige to tan, half-scored tablets, containing 57 mg firocoxib. EQUIOXX Tablets are supplied in 60 and 180 count bottles.

Authorization status:

New Animal Drug Application

Summary of Product characteristics

EQUIOXX- FIROCOXIB TABLET, CHEWABLE
MERIAL, INC.
----------
EQUIOXX
(FIROCOXIB) TABLETS
57 MG
CAUTION: Federal (USA) law restricts this drug to use by or on the
order of a licensed veterinarian.
DES CRIPTION:
EQUIOXX (firocoxib) Tablets belongs to the coxib class of
non-narcotic, non-steroidal anti-
inflammatory drugs (NSAIDs). Firocoxib is a white crystalline compound
described chemically as 3
(cyclopropylmethoxy)-4-(4-methylsulfonyl)phenyl)-5,5-dimethylfuranone.
The empirical formula is
C17H20O5S, and the molecular weight is 336.4 g/mol. The structural
formula is shown below:
INDICATIONS :
EQUIOXX Tablets are administered once daily for up to 14 days for the
control of pain and
inflammation associated with osteoarthritis in horses.
DOSAGE AND ADMINISTRATION:
Always provide the Client Information Sheet with the prescription. The
recommended dosage of
EQUIOXX Tablets is one 57 mg tablet administered orally to horses
weighing 800 – 1300 lbs, once
daily for up to 14 days. For ease of administration, EQUIOXX Tablets
may be given with food.
The overall duration of treatment with any firocoxib formulation in
horses, including EQUIOXX
Tablets, Injection or Oral Paste, should not exceed 14 days. Please
see the package insert for
EQUIOXX Injection or Oral Paste for appropriate prescribing
information for those formulations.
CONTRAINDICATIONS :
Horses with a hypersensitivity to firocoxib should not receive
EQUIOXX® Tablets.
WARNINGS :
FOR USE IN HORSES ONLY. DO NOT USE IN HORSES INTENDED FOR HUMAN
CONSUMPTION. Store EQUIOXX
Tablets out of the reach of dogs and other pets in a secured location
in order to prevent accidental
ingestion or overdose.
®
HUMAN WARNINGS: Not for use in humans. Keep this and all medications
out of the reach of children.
Consult a physician in case of accidental ingestion by humans.
PRECAUTIONS :
Horses should undergo a thorough history and physical examination
before initiation of NSAID
therapy. Appropriate laboratory tests should be conducted to establish
hematological and serum
biochemical b