PRELONE SYRUP 3MG5ML

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

PREDNISOLONE

Available from:

SUNWARD PHARMACEUTICAL SDN. BHD.

INN (International Name):

PREDNISOLONE

Units in package:

120 ml; 100 ml; 60 ml; 3800 ml; 3600 ml; 120 ml; 60 ml; 100 ml

Manufactured by:

SUNWARD PHARMACEUTICAL SDN. BHD.

Patient Information leaflet

PRELONE SYRUP
Prednisolone (3mg/5ml) 1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1. What Prelone Syrup is used for
2. How Prelone Syrup works
3. Before you use Prelone Syrup
4. How to use Prelone Syrup
5. While you are using it
6. Side effects
7. Storage and Disposal of Prelone Syrup
8. Product Description
9. Manufacturer and Product Registration
Holder
10. Date of revision
WHAT PRELONE SYRUP IS USED FOR
It is used for disease such as lack of
cortisol
hormone,
severe
allergies,
asthma,
skin
problems,
“auto-immune”
diseases,
cancer
diseases,
swelling
states
and
gastrointestinal diseases.
HOW PRELONE SYRUP WORKS
Prednisolone is known as corticosteroid or
steroid.
It
helps
by
reducing
inflammation
effect in many diseases and disorders.
BEFORE YOU USE PRELONE SYRUP
_- When you must not use it _
Do not use Prelone Syrup if:-

you have fungal infections.

you have hypersensitivity to prednisolone
or any ingredients listed at the end of this
leaflet.
_- Before you start to use it _
You should check with your doctor if you
have the following :-

congestive heart failure

diabetes

long term kidney failure

high blood pressure

recent intestinal operation

infectious diseases

muscle weakness

eye infection due to herpes simplex virus

tuberculosis disease (bacterial infection
that mainly affects the lungs)

systemic
sclerosis
(an
autoimmune
disorder). Taking daily doses of 15 mg or
more may increase the risk of a serious
complication
called
scleroderma
renal
crisis which may cause your blood pressure
to increase and reduce urination.
Some medicines may increase the effects of
Prelone Syrup and your doctor may wish to
monitor you carefully if you are taking these
medicines
(including
some
medicines
for
HIV such as cobicistat).
Prolonged use of corticosteroids may produce
cataracts (clouding of eye lens) and glaucoma
(increased pressure in the eye) with possible
damage to the optic nerves, and may increase
the risk of secondary eye infections due to
f

Summary of Product characteristics

PHARMACOLOGY:
Naturally occurring glucocorticoids (hydrocortisone and cortisone),
which also have salt-retaining
properties, are used as replacement therapy in adrenocortical
deficiency states. Their synthetic
analogs such as prednisolone are primarily used for their potent
anti-inflammatory effects in
disorders of many organ systems.
In addition, prednisolone cause profound and varied metabolic effects.
The pharmacologic effects
include action on the electrolyte balance, gluconeogenesis, lipolysis,
protein catabolism, the
action on tissue repair and healing, and the secretion of
corticotrophin by the anterior lobe of the
pituitary gland, glucose utilization and anti-insulin activity.
Peak plasma concentrations of prednisolone are obtained 1 or 2 hours
after administration by
mouth, and it has a usual plasma half-life of 2 to 4 hours. Its
initial absorption, but not its overall
bioavailability, is affected by food.
Prednisolone is extensively bound to plasma proteins, although less so
than hydrcortisone
(cortisol).
Prednisolone is excreted in the urine as free and conjugated
metabolites, together with an
appreciable proportion of unchanged prednisolone.
Prednisolone has a biological half-life lasting several hours,
intermediate between those of
hydrocortisone (cortisol) and the longer-acting glucocorticoids, such
as dexamethasone.
INDICATIONS:
It is indicated for primary or secondary adrenocortical insufficiency,
rheumatic disorders, collagen
diseases (systemic lupus erythematosus), dermatologic diseases
(pemphigus, severe psoriasis,
severe seborrheic dermatitis), bronchial asthma, ophthalmic diseases
(eye inflammation, herpes
zoster
ophthalmicus,
allergic
conjunctivitis),
hematologic
disorders,
neoplastic
diseases
(leukemias), edematous states and gastrointestinal diseases ulcerative
colitis.
DOSAGE:
Oral administration.
Dosage of Prelone Syrup should be individualized according to the
severity of the diseases and
the response of the patient. For infants and children, the recommended
dosage should be
governed by