SAFE-GUARD- fenbendazole paste

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

Fenbendazole (UNII: 621BVT9M36) (Fenbendazole - UNII:621BVT9M36)

Available from:

Merck Sharp & Dohme

INN (International Name):

Fenbendazole

Composition:

Fenbendazole 100 mg in 1 g

Administration route:

ORAL

Prescription type:

OTC

Therapeutic indications:

Horses: For the treatment and control of large strongyles (Strongylus edentatus, S. equinus, S. vulgaris ), encysted early 3rd stage (hypobiotic), late 3rd stage and 4th stage cyathostome larvae, small strongyles, pinworms (Oxyuris equi ), ascarids (Parascaris equorum ), and for the control of arteritis caused by 4th stage larvae of Strongylus vulgaris in horses. Beef and Dairy Cattle: For the treatment and control of: Lungworms: Adult Dictyocaulus viviparus ; Stomach worms: Adult brown stomach worms (Ostertagia ostertagi ), Adult and fourth stage larvae barberpole worms (Haemonchus contortus ), fourth stage larvae barberpole worms (H. placei ), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei ); Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum ), thread-necked intestinal worms (Nematodirus helvetianus ), small intestinal worms (Cooperia punctata & C. oncophora ), bankrupt worms (Trichostrongylus colubriformis ), and nodular worms (Oesophagosto

Product summary:

Safe-Guard® Paste 10% Horse and Cattle Dewormer is supplied in 92 gram syringes. Store at or below 25°C (77°F). CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT AND CONTROL OF PARASITISM.

Authorization status:

New Animal Drug Application

Summary of Product characteristics

SAFE-GUARD- FENBENDAZOLE PASTE
MERCK SHARP & DOHME
----------
SAFE-GUARD
(FENBENDAZOLE)
Paste 10% (100 mg/g)
HORSE AND CATTLE DEWORMER
396663 R13
DESCRIPTION:
Safe-Guard (fenbendazole) Paste 10% contains the active anthelmintic,
fenbendazole.
The chemical name of fenbendazole is methyl
5-(phenyl-thio)-2-benzimidazole
carbamate.
The CAS Registry Number is 43210-67-9.
The chemical structure is:
Each gram of Safe-Guard Paste 10% contains 100 mg of fenbendazole and
is flavored
with artificial apple-cinnamon liquid.
ACTIONS:
The antiparasitic action of Safe-Guard Paste 10% is believed to be due
to the inhibition
of energy metabolism in the parasite.
INDICATIONS:
HORSES: For the treatment and control of large strongyles (_Strongylus
edentatus, S._
_equinus, S. vulgaris_), encysted early 3rd stage (hypobiotic), late
3rd stage and 4th stage
cyathostome larvae, small strongyles, pinworms (_Oxyuris equi_),
ascarids (_Parascaris_
_equorum_), and for the control of arteritis caused by 4th stage
larvae of _Strongylus_
_vulgaris_ in horses.
BEEF AND DAIRY CATTLE: For the treatment and control of: Lungworms:
Adult
_Dictyocaulus viviparus_; Stomach worms: Adult brown stomach worms
(_Ostertagia_
_ostertagi_), Adult and fourth stage larvae barberpole worms
(_Haemonchus contortus_),
fourth stage larvae barberpole worms (_H. placei_), and Adult and
fourth stage larvae
small stomach worms (_Trichostrongylus axei_); Intestinal worms (Adult
and fourth stage
larvae): hookworms (_Bunostomum phlebotomum_), thread-necked
intestinal worms
®
®
®
®
(_Nematodirus helvetianus_), small intestinal worms (_Cooperia
punctata & C. oncophora_),
bankrupt worms (_Trichostrongylus colubriformis_), and nodular worms
(_Oesophagostomum radiatum_).
One syringe deworms 4 (1,000 lb) cattle or 4 (1,000 lb) horses at a
dose of 5 mg/kg or
4 (500 lb) horses at a dose of 10 mg/kg to treat ascarid infections.
PRECAUTIONS:
HORSES: Side effects associated with Safe-Guard Paste 10% could not be
established
in well-controlled safety studies in horses with single do