SCANDONEST

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Mepivacaine hydrochloride; Adrenaline

Available from:

Specialites Septodont Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

SCANDONEST 2% SPECIAL (WITH ADRENALINE). 

SCANDONEST 3% (WITHOUT VASOCONSTRICTOR (PLAIN)). 

CONSUMER MEDICINE INFORMATION  

WHAT’S IN YOUR MEDICINE

SCANDONEST contains a local anaesthetic, Mepivacaine hydrochloride.

Two different formulations of SCANDONEST are available. One
formulation contains a vasoconstrictor called 
adrenaline. 

SCANDONEST 2% SPECIAL (WITH ADRENALINE) 

ACTIVE INGREDIENTS 

Cartridge 2.2 mL 
Cartridge 1.8 mL 
Mepivacaine hydrochloride  
44 mg 
36 mg 
Adrenaline  
22 µg 
18 µg 

OTHER INGREDIENTS: 
Sodium chloride, disodium edetate, potassium
metabisulfite, hydrochloric acid, sodium hydroxide solution, water
for 
injections. 

SCANDONEST 3% (WITHOUT VASOCONSTRICTOR (PLAIN)). 

ACTIVE INGREDIENTS 

Cartridge 2.2 mL 
Cartridge 1.8 mL 
Mepivacaine hydrochloride 
66 mg 
54 mg 

OTHER INGREDIENTS: 
Sodium chloride, Sodium hydroxide solution, water for injections. 

PRESENTATION FOR BOTH PRODUCTS: 
Box of 50 cartridges for single use, containing each 2.2 mL or 1.8
mL of solution. 

WHAT YOUR MEDICINE IS USED FOR AND HOW IT WORKS 

SCANDONEST 3% contains one active ingredient, Mepivacaine
hydrochloride, a local anaesthetic to prevent the pain 
and is given by injection to cause loss of feeling before and during
dental procedures. 

SCANDONEST 2% SPECIAL contains two active ingredients,
Mepivacaine hydrochloride, a local anaesthetic to prevent 
the pain, and adrenaline, a vasoconstrictor, which
makes the local anaesthetic action of Mepivacaine last longer 
(Adrenaline narrows the blood vessels at the site of
injection, which keeps the anaesthetic where it’s needed for a 
longer time) and controls bleeding during the surgery.  

Your dentist will decide which SCANDONEST product
(with or without adrenaline) is best for the procedure. 
1 

ADVICE BEFORE USING THE MEDICINAL PRODUCT 
In deciding to use a medic

Summary of Product characteristics

SCANDONEST 2% SPECIAL  &  SCANDONEST 3% 

Scandonest 2% Special : Mepivacaine hydrochloride 2% with adrenaline
1:100,000 
Scandonest 3%               : Mepivacine hydrochloride 3%  

DESCRIPTION 

SCANDONEST 2% Special is a sterile aqueous solution that
contains Mepivacaine hydrochloride 2% 
(20mg/mL)  with adrenaline 1:100,000 
SCANDONEST 3% is a sterile aqueous solution that contains Mepivacaine
hydrochloride 3% 
(30mg/mL)  

MEPIVACAINE HYDROCHLORIDE 
CAS [1722-62-9] 
MW : 282.81 
Chemical name : 
(1-Methyl-2-piperidyl)formo-2´,6´-xylidide hydrochloride 

Chemical formula : 
C
15
H
22
N
2
O,HCl

White crystalline powder, freely soluble in water and in alcohol,
very slightly soluble in 
dichloromethane. 

Mepivacaine hydrochloride is a local anaesthetic and is a
racemic mixture. 

ADRENALINE  

CAS [51-43-4]  
MW : 183.2 

Chemical name :  
(R)-1-(3,4-di-hydroxyphenyl)-2-methylaminoethanol  

Chemical formula :  C
9
H
13
NO
3

A white to greyish-white, crystalline powder, sparingly soluble
in water, practically insoluble in alcohol 
and ether.  

Adrenaline is a vasoconstrictor  
1 

2 

QUALITATIVE AND QUANTITATIVE COMPOSITION 

SCANDONEST 2% SPECIAL  

CARTRIDGE  2.2 ML 
CARTRIDGE  1.8 ML 
ACTIVE INGREDIENTS 

Mepivacaine hydrochloride 
44 mg 
36 mg 
Adrenaline  
22 µg 
18 µg 
OTHER INGREDIENTS 

Sodium chloride 
14.3 mg 
11.7 mg 
Potassium metabisulfite 
2.64 mg 
2.16 mg 
Disodium edetate 
0.55 mg 
0.45 mg 
Sodium hydroxide solution 
(for pH adjustment) 
(for pH adjustment) 
Hydrochloric acid 
(for pH adjustment) 
(for pH adjustment) 
Water for injections q.s.  
2.2 mL 
1.8 mL 

SCANDONEST 3%  

CARTRIDGE  2.2 ML 
CARTRIDGE  1.8 ML 
ACTIVE INGREDIENTS 

Mepivacaine hydrochloride 
66 mg 
54 mg 
OTHER INGREDIENTS 

Sodium chloride 
13.2 mg 
10.8 mg 
Sodium hydroxide solution 
(for pH adjustm