Country: United States
Language: English
Source: NLM (National Library of Medicine)
MILBEMYCIN OXIME (UNII: 0502PUN0GT) (MILBEMYCIN OXIME - UNII:0502PUN0GT), LUFENURON (UNII: 1R754M4918) (LUFENURON - UNII:1R754M4918), PRAZIQUANTEL (UNII: 6490C9U457) (PRAZIQUANTEL - UNII:6490C9U457)
Virbac AH, Inc
MILBEMYCIN OXIME
MILBEMYCIN OXIME 23 mg
ORAL
PRESCRIPTION
SENTINEL SPECTRUM is indicated for the prevention of heartworm disease caused by Dirofilaria immitis ; for the prevention and control of flea populations (Ctenocephalides felis ); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult hookworm (Ancylostoma canium ), adult whipworm (Trichuris vulpis), and adult tapeworm (Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus ) infections in dogs and puppies, two pounds of body weight or greater and six weeks of age and older. There are no known contraindications to the use of SENTINEL SPECTRUM.
SENTINEL SPECTRUM is available in four strengths formulated according to the weight of the dog. Each strength is available in color-coded packages of six or twelve chewable tablets each. Manufactured for: Virbac AH, Inc. P.O. Box 162059, Ft Worth, TX 76161 NADA #141-333, Approved by FDA © 2015 Virbac Corporation. All Rights Reserved. SENTINEL and SPECTRUM are registered trademarks of Virbac Corporation.
New Animal Drug Application
SENTINEL SPECTRUM 50.1-100LBS- MILBEMYCIN OXIME, LUFENURON, PRAZIQUANTEL TABLET, CHEWABLE VIRBAC AH, INC ---------- SENTINEL SPECTRUM 50.1-100LBS CAUTION Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DES CRIPTION SENTINEL® SPECTRUM® is available in four strengths in color-coded packages for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum of 0.23 mg/pound (0.5 mg/kg) of milbemycin oxime, 4.55 mg/pound (10 mg/kg) body weight of lufenuron, and 2.28 mg/pound (5mg/kg) of praziquantel. Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A (C H NO , MW 555.71) and 20% A (C H NO , MW 541.68). Milbemycin oxime is classified as a macrocyclic anthelmintic. Lufenuron is a benzoylphenylurea derivative with the following chemical composition: N-[2,5- dichloro-4-(1,1,2,3,3,3, - hexafluoropropoxy)-phenylaminocarbonyl-2,6-difluorobenzamide (C H Cl F N O , MW 551.15). Benzoylphenylurea compounds, including lufenuron, are classified as insect development inhibitors (lDIs). Praziquantel is an isoquinolone anthelmintic with the chemical name 2-(Cyclohexylcarbonyl)-1 ,2,3,6,7,- 11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one. SENTINEL SPECTRUM is indicated for the prevention of heartworm disease caused by _Dirofilaria_ _immitis_; for the prevention and control of flea populations (_Ctenocephalides felis_); and for the treatment and control of adult roundworm (_Toxocara canis, Toxascaris leonina_), adult hookworm (_Ancylostoma_ _canium_), adult whipworm (Trichuris vulpis), and adult tapeworm (_Taenia pisiformis, Echinococcus_ _multilocularis_ and _Echinococcus granulosus_) infections in dogs and puppies, two pounds of body weight or greater and six weeks of age and older. DOSAGE AND ADMINISTRATION SENTINEL SPECTRUM should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, 4.55 mg/lb (10mg/k Read the complete document