THIDEXAVET- thiabendazole, dexamethasone, neomycin sulfate solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

THIABENDAZOLE (UNII: N1Q45E87DT) (THIABENDAZOLE - UNII:N1Q45E87DT)

Available from:

Dechra Veterinary Products

INN (International Name):

THIABENDAZOLE

Composition:

THIABENDAZOLE 40 mg in 1 mL

Administration route:

AURICULAR (OTIC)

Prescription type:

PRESCRIPTION

Therapeutic indications:

INDICATIONS: Dermatologic Solution ThiDexaVet Solution is indicated as an aid in the treatment of certain bacterial, mycotic, and inflammatory dermatoses and otitis externa in dogs and cats. Both acute and chronic forms of these skin disorders respond to treatment with ThiDexaVet Solution. Many forms of dermatosis are caused by bacteria (chiefly Staphylococcus aureus , Proteus vulgaris  and Pseudomonas aeruginosa ). Moreover, these organisms often act as opportunistic or concurrent pathogens that may complicate already established mycotic skin disorders, or otoacariasis caused by Otodectes cynotis . The principal etiologic agents of dermatomycoses in dogs and cats are species of the genera Microsporum  and Trichophyton . The ef­ficacy of neomycin as an antibacterial agent, with activity against both gram-negative and gram-positive pathogens, is well documented. Detailed studies in various laboratories have verifi­ed the signifi­cant activity thiabendazole displays against the important dermatophytes. Dexameth

Product summary:

HOW SUPPLIED: Dermatologic Solution ThiDexaVet Solution is supplied in 7.5 mL (NDC 17033-207-76) and 15 mL (17033-207-56) dropper bottles, each in 6 bottle boxes.

Authorization status:

Abbreviated New Animal Drug Application

Summary of Product characteristics

THIDEXAVET- THIABENDAZOLE, DEXAMETHASONE, NEOMYCIN SULFATE SOLUTION
DECHRA VETERINARY PRODUCTS
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ANADA 200-565, Approved by FDA
THIDEXAVET SOLUTION (THIABENDAZOLE, DEXAMETHASONE, NEOMYCIN SULFATE SOLUTION)
DERMATOLOGIC SOLUTION
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION:
Dermatologic Solution ThiDexaVet Solution contains the following
active ingredients per mL: 40 mg
thiabendazole, 1 mg dexamethasone, 3.2 mg neomycin (from neomycin
sulfate). Inactive ingredients:
glycerin, propylene glycol, purifed water, hypophosphorous acid,
calcium hypophosphite; about 8.5%
ethyl alcohol and about 0.5% benzyl alcohol.
INDICATIONS:
Dermatologic Solution ThiDexaVet Solution is indicated as an aid in
the treatment of certain bacterial,
mycotic, and inflammatory dermatoses and otitis externa in dogs and
cats. Both acute and chronic forms
of these skin disorders respond to treatment with ThiDexaVet Solution.
Many forms of dermatosis are
caused by bacteria (chiefly _Staphylococcus aureus_, _Proteus
vulgaris_ and _Pseudomonas aeruginosa_).
Moreover, these organisms often act as opportunistic or concurrent
pathogens that may complicate
already established mycotic skin disorders, or otoacariasis caused by
_Otodectes cynotis_. The principal
etiologic agents of dermatomycoses in dogs and cats are species of the
genera _Microsporum_ and _Trichophyton_. The efficacy of neomycin as
an antibacterial agent, with activity
against both gram-negative and gram-positive pathogens, is well
documented. Detailed studies in
various laboratories have verified the significant activity
thiabendazole displays against the important
dermatophytes. Dexamethasone, a synthetic adrenocorticoid steroid,
inhibits the reaction of connective
tissue to injury and suppresses the classic inflammatory
manifestations of skin disease. The formulation
for ThiDexaVet Solution combines these several activities in a
complementary form for control of the
discomfort and direct treatment of dermatitis and