POTASSIUM CITRATE, SODIUM CITRATE, AND CITRIC ACID- potassium citrate, sodium citrate, and citric acid monohydrate solution

Riik: Ameerika Ühendriigid

keel: inglise

Allikas: NLM (National Library of Medicine)

Toimeaine:

POTASSIUM CITRATE (UNII: EE90ONI6FF) (ANHYDROUS CITRIC ACID - UNII:XF417D3PSL), SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR) (ANHYDROUS CITRIC ACID - UNII:XF417D3PSL), CITRIC ACID MONOHYDRATE (UNII: 2968PHW8QP) (ANHYDROUS CITRIC ACID - UNII:XF417D3PSL)

Saadav alates:

Westminster Pharmaceuticals, LLC

Manustamisviis:

ORAL

Retsepti tüüp:

PRESCRIPTION DRUG

Näidustused:

Potassium Citrate, Sodium Citrate and Citric Acid Oral Solution is an effective alkalinizing agent useful in those conditions where long-term maintenance of an alkaline urine is desirable, such as in patients with uric acid and cystine calculi of the urinary tract. In addition, it is a valuable adjuvant when administered with uricosuric agents in gout therapy, since urates tend to crystallize out of an acid urine. It is also effective in correcting the acidosis of certain renal tubular disorders. This product is highly concentrated and when administered after meals and before bedtime, allows one to maintain an alkaline urine pH around the clock, usually without the necessity of a 2 A.M. dose. This product alkalinizes the urine without producing a systemic alkalosis in recommended dosages. It is highly palatable, pleasant tasting, and tolerable, even when administered for long periods. Potassium citrate and sodium citrate do not neutralize the gastric juice or disturb digestion. Severe renal impairment with ol

Toote kokkuvõte:

Potassium Citrate, Sodium Citrate and Citric Acid Oral Solution (orange colored, raspberry flavored) is supplied in the following form: NDC 69367-322-16 (16 fl oz bottles). Keep tightly closed. Store at controlled room temperature, 20°-25° C (68° - 77°F). Protect from excessive heat and freezing. Tamper evident by foil seal under cap. Do not use if foil seal is broken or missing. Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure. KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN. IN CASE OF ACCIDENTAL OVERDOSAGE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY.

Volitamisolek:

unapproved drug other

Toote omadused

POTASSIUM CITRATE, SODIUM CITRATE, AND CITRIC ACID- POTASSIUM CITRATE,
SODIUM CITRATE, AND CITRIC ACID MONOHYDRATE SOLUTION
WESTMINSTER PHARMACEUTICALS, LLC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this_
_labeling has not been approved by FDA. For further information about
unapproved_
_drugs, click here._
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POTASSIUM CITRATE, SODIUM CITRATE AND CITRIC ACID ORAL SOLUTION
RX ONLY
NDC 69367-322-16
DESCRIPTION
Potassium Citrate, Sodium Citrate and Citric Acid Oral Solution is a
stable and pleasant-
tasting oral systemic alkalizer containing potassium citrate, sodium
citrate, and citric acid
in a sugar-free, non alcoholic base.
Potassium Citrate, Sodium Citrate, and Citric Acid Oral Solution
contains in each
teaspoonful (5 mL):
Potassium Citrate
Monohydrate
550 mg
Sodium Citrate Dihydrate
500 mg
Citric Acid Monohydrate
334 mg
Each mL contains 1 mEq potassium ion and 1 mEq sodium ion and is
equivalent to 2
mEq bicarbonate (HCO ).
INACTIVE INGREDIENTS
FD&C yellow #6, purified water, raspberry flavor, sodium benzoate,
sodium saccharin,
sorbital solution.
POTASSIUM CITRATE MONOHYDRATE has the chemical name:
1,2,3-Propanetricarboxylic
acid, 2-hydroxy-, tripotassium salt, monohydrate. Its chemical
structure is as follows
C H K O + H O M.W. 324.41
SODIUM CITRATE DIHYDRATE has the chemical name:
1,2,3-Propanetricarboxylic acid, 2-
3
6 5 3
7
2
hydroxy-, trisodium salt, dihydrate. Its chemical structure is as
follows.
C H NA O + 2H O M.W. 294.10
CITRIC ACID MONOHYDRATE has the chemical name:
1,2,3-Propanetricarboxylic acid, 2-
hydroxy-,monohydrate. Its chemical structure is as follows.
C H O + H O M.W. 210.14
CLINICAL PHARMACOLOGY
Potassium citrate and sodium citrate are absorbed and metabolized to
potassium
bicarbonate and sodium bicarbonate, thus acting as systemic
alkalizers. The effects are
essentially those of chlorides before absorption and those of
bicarbonates
subsequently. Oxidation is virtually complete so that less than 5% of
the citrates are
excreted in the urine unchan