Pays: Inde
Langue: anglais
Source: Central Drugs Standard Control Organization
Hydroxyprogesterone Caproate
Zydus (G.Rem)
G03DA03
250MG/ML
INJ
1
250 mg x 1 mL x 1ml
Oestrogens & Progesterones & Related Synthetic Drugs
hydroxyprogesterone
Habitual abortion, Imminent abortion, Infertility due to corpus luteum insufficiency, Primary & secondary amenorrhea
PROLUTON DEPOT 1 INJ 250MG/ML PROLUTON DEPOT 1 INJ 500MG/2ML INDICATION & DOSAGE _Intramuscular _Recurrent miscarriage _Adult: _250-500 mg wkly during the 1st half of pregnancy. _Intramuscular _Amenorrhoea _Adult: _Single dose of 375 mg; may repeat at 4-wkly intervals if needed. After 4 days of desquamation, or if there is no bleeding within 21 days after admin of the drug, may initiate cyclic therapy that includes an oestrogen. For cyclic treatment (28-day cycle): Administer 20 mg of estradiol valerate on day 1, and on day 15, administer 250 mg of hydroxyprogesterone caproate and 5 mg of estradiol valerate. May repeat cyclic therapy at 4-wkly intervals as needed. _Intramuscular _Abnormal uterine bleeding _Adult: _Single dose of 375 mg; may repeat at 4-wkly intervals if needed. After 4 days of desquamation, or if there is no bleeding within 21 days after admin of the drug, may initiate cyclic therapy that includes an oestrogen. For cyclic treatment (28-day cycle): Administer 20 mg of estradiol valerate on day 1, and on day 15, administer 250 mg of hydroxyprogesterone caproate and 5 mg of estradiol valerate. May repeat cyclic therapy at 4-wkly intervals as needed. _Intramuscular _Palliative treatment of advanced, inoperable endometrial carcinoma _Adult: _Usual dose: ≥1 g, may repeat once or more times wkly. Usual range: 1-7 g/wk. Discontinue treatment if relapse occurs or if the objective response is not achieved after 12 wk of treatment. CONTRAINDICATIONS Undiagnosed vaginal bleeding, breast cancer, pregnancy, lactation. Thrombophlebitis, thromboembolic disorders, cerebral apoplexy or a history of these conditions. Markedly impaired liver function. SPECIAL PRECAUTIONS Physical examination is advised prior to starting therapy. Hepatic impairment, mental depression. Monitor blood glucose in diabetic patients. Discontinue treatment upon signs of throm Lire le document complet