देश: संयुक्त राज्य
भाषा: अंग्रेज़ी
स्रोत: NLM (National Library of Medicine)
eprinomectin (UNII: 75KP30FD8O) (eprinomectin - UNII:75KP30FD8O)
Merial, Inc.
eprinomectin
eprinomectin 50 mg in 1 mL
SUBCUTANEOUS
PRESCRIPTION
Extended-Release Injectable Parasiticide 5% Sterile Solution For the Treatment and Control of Internal and External Parasites of Cattle on Pasture with Persistent Effectiveness Not for use in female dairy cattle 20 months of age or older, including dry dairy cows. Not for use in calves to be processed for veal. Not for use in breeding bulls, or in calves less than 3 months of age. Not for use in cattle managed in feedlots or under intensive rotational grazing. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. LONGRANGE, when administered at the recommended dose volume of 1 mL per 110 lb (50 kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle: Persistent Activity LONGRANGE has been proven to effectively protect cattle from reinfection with the following parasites for the indicated amounts of time following treatment:
LONGRANGE is available in three ready-to-use glass bottle sizes. The 100, 250 and 500 mL bottles contain sufficient solution to treat 20, 50 and 100 head of 550 lb (250 kg) cattle, respectively. The 250 and 500 mL bottles are supplied in a removable plastic protector. Store at 77° F (25° C) with excursions between 59° and 86° F (15° and 30° C). Protect from light.
New Animal Drug Application
LONGRANGE- EPRINOMECTIN INJECTION, SOLUTION MERIAL, INC. ---------- LONGRANGE (EPRINOMECTIN) Extended-Release Injectable Parasiticide 5% Sterile Solution For the Treatment and Control of Internal and External Parasites of Cattle on Pasture with Persistent Effectiveness NOT FOR USE IN FEMALE DAIRY CATTLE 20 MONTHS OF AGE OR OLDER, INCLUDING DRY DAIRY COWS. NOT FOR USE IN CALVES TO BE PROCESSED FOR VEAL. NOT FOR USE IN BREEDING BULLS, OR IN CALVES LESS THAN 3 MONTHS OF AGE. NOT FOR USE IN CATTLE MANAGED IN FEEDLOTS OR UNDER INTENSIVE ROTATIONAL GRAZING. CAUTION: FEDERAL LAW RESTRICTS THIS DRUG TO USE BY OR ON THE ORDER OF A LICENSED VETERINARIAN. DESCRIPTION LONGRANGE (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness. Butylated hydroxytoluene (0.2 mg/mL) acts as an antioxidant in the formulation. The chemical name of eprinomectin is 4"-deoxy-4"-epiacetylamino-avermectin B . It is a semi- synthetic member of the avermectin family of compounds consisting of a mixture of two homologous components, B and B , which differ by a single methylene group at C . INDICATIONS FOR USE LONGRANGE, when administered at the recommended dose volume of 1 mL per 110 lb (50 kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle: ® ® 1 1a 1b 26 GASTROINTESTINAL ROUNDWORMS LUNGWORMS _Bunostomum phlebotomum_ – Adults and L _Dictyocaulus viviparus_ – Adults _Cooperia oncophora_ – Adults and L _Cooperia punctata_ – Adults and L _Cooperia surnabada_ – Adults and L GRUBS _Haemonchus placei_ – Adults _Hypoderma bovis_ _Oesophagostomum radia पूरा दस्तावेज़ पढ़ें