MALTOFER DROPS 50 mgml

देश: सिंगापुर

भाषा: अंग्रेज़ी

स्रोत: HSA (Health Sciences Authority)

सक्रिय संघटक:

IRON HYDROXIDE POLYMALTOSE EQV IRON

थमां उपलब्ध:

VIFOR PHARMA ASIA PACIFIC PTE. LTD.

ए.टी.सी कोड:

B03AB05

डोज़:

50 mg/ml

फार्मास्यूटिकल फॉर्म:

SOLUTION

रचना:

IRON HYDROXIDE POLYMALTOSE EQV IRON 50 mg/ml

प्रशासन का मार्ग:

ORAL

प्रिस्क्रिप्शन प्रकार:

General Sale List

द्वारा बनाया गया:

VIFOR SA

प्राधिकरण का दर्जा:

ACTIVE

प्राधिकरण की तारीख:

1991-04-08

सूचना पत्रक

107157 
Pf 427-00
DROPS
Pharmaceutical form: oral solution
COMPOSITION
1 ml (20 drops) contains 50 mg of iron as 
Iron(III)-Hydroxide Poly maltose Complex 
(IPC),  flavouring, sucrose, preservatives 
(E 217, E 219), excip. ad solutionem.
PROPERTIES
Pharmacotherapeutical group: 
Antianaemicum.
ATC Code: B03AB05
Maltofer
®
 drops is an iron prepara tion for 
the  treatment  of  latent  iron  deficiency 
and iron deficiency anaemia. Iron is an 
important  constituent  of  haemoglobin, 
myoglobin, and the enzymes which con-
tain iron. The treatment of iron deficiency 
in  infants  up  to  one  year  of  age  is  of 
extreme  importance.  Iron  deficiency  at 
this age can impair the development of 
the brain. In general, iron deficiency can 
cause chronic fatigue, lack of concentra-
tion, irritability, nervousness, headache, 
loss of appetite, susceptibility to stress 
and  infection,  pale ness,  cracks  at  the 
corners  of  the  mouth  (rhagades),  dry 
skin, brittle hair and nails as well as loss 
of interest in play in children.
The iron in Maltofer
®
 drops is present as 
Iron(III)-Hydroxide Complex, where indi-
vi d ual particles are embedded in a car-
bohydrate  polymer  (polymaltose).  This 
prevents the iron from causing any harm 
in the gastro intestinal system. This pro-
tection  inhibits  interactions  of  the  iron 
with food. Moreover, it ensures the bio-
availability of the iron.
The structure of IPC is similar to ferritin, 
the naturally occurring iron storage pro-
tein.  Due  to  this  similarity,  iron  is  ab -
sorbed through natural mechanisms.
IPC has no pro-oxidative properties such 
as there are with bivalent iron salts.
INDICATIONS
Treatment  of  latent  iron  deficiency  and 
iron  deficiency  anaemia  (manifest  iron 
def

उत्पाद विशेषताएं

2020-06-17 SG MAL DR PI_v.2
MALTOFER®
DROPS
Pharmaceutical form: oral solution
Qualitative and quantitative composition1 ml (20 drops) contains 50 mg
of iron as iron(III)-hydroxide
polymaltose complex (IPC).
Excipients: purified water, sucrose, cream essence, sodium methyl
hydroxybenzoate (E219), sodium
propyl hydroxybenzoate (E217) and sodium hydroxide.
PROPERTIES/EFFECTS
Pharmacotherapeutical group: iron preparation.
ATC Code: B03AB05
Maltofer® drops are an iron preparation for the treatment of iron
deficiency without anaemia and
iron deficiency anaemia.
Iron is an important constituent of haemoglobin, myoglobin, and
iron-containing enzymes. In
general, iron deficiency can cause chronic fatigue, lack of
concentration and reduced mental
performance, irritability, anxiety, headache, loss of appetite,
susceptibility to infection, conspicuous
paleness, cracks at the corners of the mouth (rhagades), dry skin and
brittle hair and nails.
In the iron(III)-hydroxide polymaltose complex, the polynuclear
iron(III)-hydroxide core is superficially
surrounded by a number of non-covalently bound polymaltose molecules
resulting in an overall
average molecular weight of approximately 50 kDa. The polynuclear core
of IPC has a structure similar
to that of the physiological iron storage protein, ferritin. IPC is a
stable complex and does not release
large amounts of iron under physiological conditions. Because of its
size, the extent of diffusion of IPC
through the membrane of the mucosa is about 40 times less than that of
the hexaquo-iron(II) complex.
Iron from IPC is taken up in the gut via an active mechanism. In
contrast to iron(II) salts, IPC does not
have pro-oxidative properties.
_Pharmacodynamics _
The iron absorbed is bound to transferrin and is used for Hb synthesis
in the bone
marrow or stored primarily in the liver bound to ferritin.
_Clinical Efficacy _
The efficacy of Maltofer compared to a placebo or similar preparations
with different iron
formulations in terms of normalising haemoglobin values and
replenishing i