Država: Armenija
Jezik: engleski
Izvor: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում
tretinoin
Arpimed LLC
D10AD01
tretinoin
0,5mg/ml
solution for topical use
30ml glass bottle
OTC
Registered
2018-09-12
SUMMARY PRODUCT CHARACTERISTIC {SPC} SILKADEBM 0.05% solution for foPical use COMPO$ITION Each mt of $ILKAIIERM solution contains: s€tive ingrcdient: ffetinoin - 0.5 mg; furctive ingredients,: a-tocopheryl acetate (viamin E), propylene glycol, etlranol 96%. PHARMACOLOGICAL GROUP AND ATC CODE Dermatological drug retinoid; D I 0AD0l . PHARMACEUTICAL FORM Soluticn for topical use. A transparent, yellow tiquid. PHARMACOLOCY Tretinoin is a retinoid and is the acid form of vitamin A' Tretinoin is used prirnarity in the topical featmsnt of acne vulgaris when comedones, papules, and pustules predaminate- lt appears ta stimulate mitosis ald turnover of follicular epithelial cells end reduce their cahesiveness thereby facilitating the extr*sion of existing cornedones and preventing the farmation of new ones. It also appears to have a thinning effect on the stratum corneum. PHARMACOKINETICS Absorption does not sesm to cccur to any great extent with topical use. USES AIYD ADMINISTRATION Silkaderm is used prim*rily in the topical treatment of aene vulgaris when comedones, papules, and pustules predominate. Silkaderm is also use{ for tlre treatment of mottled hyperpigmentation, roughness, and fine wrinkling of photodamaged skin. Administration Silkaderm is applied topically to the skin. Patients should be instrueted carefully in proper use of the drug ineluding associated precautions. The skin should be cleansed to remove excsssive oiliness and dried 15 ts 30 minutes before applying tretinoin lightly, once sr fwice daily according to response and irritatioll; some patients may require less frequent applications. Other topical preparations {including skin moisturisen) should not be applied at the same time as ketinoin is applied, and eaution is required if other local irritants are used concurrently, There may be apparent exacerbafions of the acne during early treatrnent and a therapeutic rcsponse may not be evident far 6 to I weeks. When fhe condition has resolved maintenance therapy should be less fiequent. For the treatmen Pročitajte cijeli dokument