Ország: Egyesült Államok
Nyelv: angol
Forrás: NLM (National Library of Medicine)
Gentamicin Sulfate (UNII: 8X7386QRLV) (Gentamicin - UNII:T6Z9V48IKG)
Akorn
Gentamicin Sulfate
Gentamicin 3 mg in 1 mL
OPHTHALMIC
PRESCRIPTION
Gentamicin Sulfate Ophthalmic Solution is indicated for topical treatment of conjunctivitis caused by susceptible bacteria in dogs and cats.
Gentamicin Sulfate Ophthalmic Solution is supplied in a white low density polyethylene plastic squeeze bottle with a white controlled dropper tip and a white polypropylene cap in the following sizes: NDC 59399-101-05 5 mL; box of one Store solution at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].
Abbreviated New Animal Drug Application
GENTAMICIN SULFATE- GENTAMICIN SULFATE SOLUTION/ DROPS AKORN ---------- Gentamicin Sulfate Ophthalmic Solution Sterile ANADA 200-576, Approved by FDA VETERINARY FOR USE IN DOGS AND CATS DESCRIPTION: Gentamicin sulfate is a water soluble antibiotic of the aminoglycoside group active against a wide variety of pathogenic gram-negative and gram-positive bacteria. Gentamicin Sulfate Ophthalmic Solution is a sterile aqueous solution for use in the eye. Each mL contains: Active: Gentamicin Sulfate USP (equivalent to 3 mg gentamicin base). Inactives: 2.9 mg Disodium Phosphate, 0.1 mg Monosodium Phosphate, and 7.40 mg Sodium Chloride. The pH range is from 6.8 to 7.3. Preservative: 0.1 mg Benzalkonium Chloride as preservative. CHEMISTRY: Gentamicin is an aminoglycoside antibiotic mixture derived from _Micromonospora_ _purpurea_ of the Actinomycetes group. It is a powder, white to buff in color, readily soluble in water, and heat stable. ACTION: Gentamicin sulfate, a broad spectrum antibiotic, is a highly effective topical treatment in primary and secondary bacterial infections of the eye and surrounding tissues. Gentamicin is bactericidal _in vitro_ against a wide variety of gram-positive and gram- negative bacteria. Concentrations of gentamicin sulfate required to inhibit growth of gram-positive and gram-negative clinical and laboratory strains of bacteria tested were less than those of neomycin in most instances. Gentamicin is active against most gram-negative bacteria including _Pseudomonas aeruginosa_, indole positive and negative _Proteus_ species, _Escherichia coli, Klebsiella_ sp. and _Enterobacter_ sp. Gentamicin is also active against strains of gram-positive bacteria including _Staphylococcus_ species and _Streptococcus_ species. INDICATIONS: Gentamicin Sulfate Ophthalmic Solution is indicated for topical treatment of conjunctivitis caused by susceptible bacteria in dogs and cats. DOSAGE AND ADMINISTRATION: Gentamicin Sulfate Ophthalmic Solution-1 or 2 drops instilled into the conjunctival sac 2 1,2 to 4 times a Olvassa el a teljes dokumentumot