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MAYNE PHARMA ERYTHROMYCIN
CAPSULES
erythromycin _(eh-rith-roe-MYE-sin) _
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CONSUMER MEDICINE INFORMATION
_Date of Dispensing _
_Consumer Name _
_Pharmacist Name _
_Consumer Address _
_Pharmacist Address _
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Mayne Pharma
Erythromycin Capsules. It does not
contain all the available information.
It does not take the place of talking
to your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking erythromycin
against the benefits they expect it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE
MEDICINE.
You may need to read it again.
WHAT ERYTHROMYCIN
CAPSULES ARE USED FOR
This medicine is an antibiotic used
to:
treat infections in different parts
of the body caused by bacteria
prevent infections in patients
with a history of rheumatic
disease who may be allergic to
penicillin.
This medicine is an antibiotic which
belongs to a group of medicines
called macrolides.
It works by killing or stopping the
growth of bacteria which cause
infections.
This medicine will not work against
viral infections such as colds or flu.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS
MEDICINE HAS BEEN PRESCRIBED FOR
YOU.
Your doctor may have prescribed it
for another reason.
This medicine is not addictive.
This medicine is available only with
a doctor’s prescription.
BEFORE YOU TAKE
ERYTHROMYCIN CAPSULES
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_WHEN YOU MUST NOT TAKE IT _
DO NOT TAKE ERYTHROMYCIN
CAPSULES IF YOU HAVE AN ALLERGY
TO:
any medicine containing
erythromycin
any of the ingredients listed at
the end of this leaflet.
Some of the symptoms of an
allergic reaction may include
shortness of breath, wheezing or
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SPC
Product Information – Australia
Version 2.0
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MAYNE PHARMA ERYTHROMYCIN CAPSULES
NAME OF THE MEDICINE
The active ingredient in Mayne Pharma Erythromycin Capsules is
erythromycin.
The chemical structure of erythromycin is shown below
CAS No. 114-07-8
DESCRIPTION
Mayne Pharma Erythromycin Capsules contain enteric coated pellets of
erythromycin for oral
administration. The enteric coating on the pellets covers the
bitter tasting erythromycin as well as protects
the erythromycin from gastric acid destruction during the passage
through the stomach.
Mayne Pharma Erythromycin Capsules also contain the
following inactive ingredients: lactose,
potassium phosphate monobasic, povidone, water-purified, cellacephate,
diethyl phthalate, gelatine,
shellac, erythrosine, indigo carmine (132), sunset yellow (110),
carbon black (153).
Erythromycin is produced by a strain of _Streptomyces erythreus_ and
belongs to the macrolide group of
antibiotics. It is basic and readily forms salts with acids.
CLINICAL PHARMACOLOGY
Orally administered erythromycin is readily absorbed in the
microbiologically active form. Interindividual
variations in the absorption of erythromycin are, however, observed
and some patients do not achieve
acceptable serum levels. Absorption may be interfered with by the
presence of food in the stomach.
Optimal conditions for stability in the presence of gastric secretion
and for complete absorption are
attained when Mayne Pharma Erythromycin Capsules are taken on an
empty stomach.
After administration of the third dose of 2 x 175mg erythromycin
capsules to adults, a mean peak serum
level of 2.01 ± 0.69mcg/ml was attained in approximately 2-4 hours.
This is comparable to peak serum
levels achieved with 2 x 250mg of other formulations of erythromycin.
Erythromycin is bound to plasma
proteins to the extent of approximately 75%. It diffuses readily
into most body fluids
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