Negara: Inggris
Bahasa: Inggris
Sumber: myHealthbox
Allopurinol
Milpharm Limited
M04AA01
Allopurinol
100mg
Tablets
Oral use
1000, 500, 250, 100, 84, 70, 56, 42, 28, 21, 15 and 14 tablets
POM - Prescription Only Medicine
Milpharm Limited
Preparations inhibiting uric acid production
It is indicated for reducing urate/uric acid formation in conditions where urate/uric acid deposition has already occurred (e.g. gouty arthritis, skin tophi, nephrolithiasis) or is a predictable clinical risk (e.g. treatment of malignancy potentially leading to acute uric acid nephropathy). The main clinical conditions where urate/uric acid deposition may occur are: idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate levels occur either spontaneously, or after cytotoxic therapy; certain enzyme disorders which lead to overproduction of urate, for example: hypoxanthine-guanine phosphoribosyltransferase, including Lesch-Nyhan syndrome; glucose-6-phosphatase including glycogen storage disease; phosphoribosylpyrophosphate synthetase, phosphoribosylpyrophosphate amidotransferase; adenine phosphoribosyltransferase. Allopurinol is indicated for management of 2,8-dihydroxyadenine (2,8-DHA) renal stones
Authorised
2009-03-02
PACKAGE LEAFLET: INFORMATION FOR THE USER ALLOPURINOL TABLETS BP 100MG (allopurinol) READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU START TAKING THIS MEDICINE. · Keep this leaflet. You may need to read it again. · If you have any further questions, ask your doctor or pharmacist. · This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. · If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. IN THIS LEAFLET: 1. What allopurinol Tablets are and what they are used for 2. Before you take Allopurinol Tablets 3. How to take Allopurinol Tablets 4. Possible side effects 5. How to store Allopurinol Tablets 6. Further information Allopurinol Tablets belong to a group of medicines called enzyme inhibitors. Allopurinol Tablets are used in: · long term prevention of gout · prevention of kidney stones · treatment of high levels of uric acid associated with tumors and their treatment · certain enzyme disorder in particular Lesch Nyhan syndrome Serious skin rashes (Hypersensitivity syndrome, Stevens- Johnson syndrome, toxic epidermal necrolysis) have been reported with the use of allopurinol. Frequently, the rash can involve ulcers of the mouth, throat, nose, genitals and conjunctivitis (red and swollen eyes). These serious skin rashes are often preceded by influenza-like symptoms fever, headache, body ache (flu-like symptoms). The rash may progress to widespread blistering and peeling of the skin. These serious skin reactions can be more common in people of Han Chinese or Thai origin. If you develop a rash or these skin symptoms, stop taking allopurinol and contact your doctor immediately. DO NOT TAKE ALLOPURINOL TABLETS IF: · you are sensitive or allergic to Allopurinol or any of the ingredients in the tablets (listed in section 6). Do not take Allopurinol Tablets if the above applies to you. If you are Baca dokumen lengkapnya
Allopurinol Milpharm 100mg Tablets Summary of Product Characteristics Updated 24Aug2015 | Aurobindo Pharma Milpharm Ltd. 1. Name of the medicinal product Allopurinol Tablets BP 100mg 2. Qualitative and quantitative composition Each tablet contains 100 mg Allopurinol. For a full list of excipients, see section 6.1. 3. Pharmaceutical form Tablets. White round tablets with convex sides, with emboss MAL 100 on one side and plain on reverse. 4. Clinical particulars 4.1 Therapeutic indications Allopurinol is indicated for reducing urate/uric acid formation in conditions where urate/uric acid deposition has already occurred (e.g. gouty arthritis, skin tophi, nephrolithiasis) or is a predictable clinical risk (e.g. treatment of malignancy potentially leading to acute uric acid nephropathy). The main clinical conditions where urate/uric acid deposition may occur are: idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate levels occur either spontaneously, or after cytotoxic therapy; certain enzyme disorders which lead to overproduction of urate, for example: hypoxanthineguanine phosphoribosyltransferase, including LeschNyhan syndrome; glucose6phosphatase including glycogen storage disease; phosphoribosylpyrophosphate synthetase, phosphoribosylpyrophosphate amidotransferase; adenine phosphoribosyltransferase. Allopurinol is indicated for management of 2,8dihydroxyadenine (2,8DHA) renal stones related to deficient activity of adenine phosphoribosyltransferase. Allopurinol is indicated for the management of recurrent mixed calcium oxalate renal stones in the presence of hyperuricosuria, when fluid, dietary and similar measures have failed. 4.2 Posology and method of administration _Dosa Baca dokumen lengkapnya