Land: Ástralía
Tungumál: enska
Heimild: Department of Health (Therapeutic Goods Administration)
amoxicillin trihydrate,potassium clavulanate
Southern Cross Pharma Pty Ltd
amoxicillin trihydrate,potassium clavulanate
________________________________________________________________________________ C:Products/Amoxyclav AN/CMI_1 31072015 Page 1 of 4 AMOXYCLAV AN _[amoxicillin trihydrate and potassium clavulanate] _ CONSUMER MEDICINE INFORMATION _ _ PLEASE READ THIS LEAFLET CAREFULLY BEFORE YOU START AMOXYCLAV AN. What is in this leaflet This leaflet answers some common questions about this medicine. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you being given this medication against the benefits it is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. What this medicine is used for Amoxyclav AN tablets contain two active ingredients. One of these is from the penicillin group of antibiotics and is called amoxicillin (from amoxicillin trihydrate) and the other is clavulanic acid (from potassium clavulanate). Amoxyclav AN tablets are used to treat a wide range of infections caused by bacteria. These infections may affect the chest (bronchitis or pneumonia), bladder (cystitis), sinuses (sinusitis), the ears (otitis media) or the skin. Amoxyclav AN tablets work by killing the bacteria that cause these infections. Amoxyclav AN tablets will not work against infections caused by viruses such as colds or the flu. Your doctor may prescribe Amoxyclav AN tablets for another use. If you want more information ask your doctor. There is no evidence that Amoxyclav AN tablets are addictive. Before you take it _Do not take Amoxyclav AN tablets if: _ _ _ you have had an allergic reaction to penicillin or similar types of antibiotics (such as cephalosporins) or any of the ingredients contained in Amoxyclav AN tablets. The ingredients are listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching, difficulty in breathing and swelling of Lestu allt skjalið
C:Products/Amoxyclav AN/PI _17072015_2 Page 1 of 17 PRODUCT INFORMATION AMOXYCLAV AN 500/125 & AMOXYCLAV AN 875/125 NAME OF THE MEDICINE PROPRIETARY NAMES: AMOXYCLAV AN 500/125 & AMOXYCLAV 875/125 TABLETS NON PROPRIETARY NAME: amoxicillin (as trihydrate) & clavulanic acid (as potassium clavulanate) tablets CHEMICAL NAMES:_ _ Amoxicillin trihydrate: (2 _S_ ,5 _R_ ,6 _R_ )-6-[( _R_ )-(-)-2-Amino-2-( _p_ –hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate. Potassium clavulanate: Potassium ( _Z_ )-(2 _R_ ,5 _R_ )-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]-heptane-2- carboxylate. MOLECULAR FORMULA AND MOLECULAR WEIGHT: Amoxicillin trihydrate – the molecular formula is C 16 H 19 N 3 O 5 S ּ ◌3H 2 O, and the molecular weight is 419.46. Potassium clavulanate – the molecular formula is C 8 H 8 KNO 5 , and the molecular weight is 237.25. STRUCTURES: _ _ The chemical structure of amoxicillin trihydrate is: C:Products/Amoxyclav AN/PI _17072015_2 Page 2 of 17 The chemical structure of potassium clavulanate is: CAS NUMBERS: Amoxicillin trihydrate - 61336-70-7, and Potassium clavulanate - 61177-45-5 _ _ DESCRIPTION Amoxicillin is a semi-synthetic antibiotic. Amoxicillin trihydrate is a white to off white crystalline powder and is slightly soluble in water. Clavulanic acid is an irreversible inhibitor of many beta-lactamase enzymes except type 1 (Richmond). It is a beta-lactam compound with only weak antibacterial activity in its own right. Potassium clavulanate is a white to off white hygroscopic crystalline powder and is freely soluble in water. Amoxyclav AN 500/125 tablet is an immediate release tablet form and each tablet contains amoxicillin (as trihydrate) equivalent to 500 mg amoxicillin and potassium clavulanate equivalent to 125 mg clavulanic acid. Amoxyclav AN 875/125 tablet is an immediate release tablet form and each tablet contains amoxicillin (as trihydrate) equivalent to 875 mg amoxicillin and potassium clavulanate equivalent to 125 mg Lestu allt skjalið