DEXAMETHASONE SP- dexamethasone sodium phosphate injection, solution

国: アメリカ合衆国

言語: 英語

ソース: NLM (National Library of Medicine)

有効成分:

Dexamethasone Sodium Phosphate (UNII: AI9376Y64P) (Dexamethasone - UNII:7S5I7G3JQL)

から入手可能:

MWI/VetOne

INN（国際名）:

Dexamethasone Sodium Phosphate

構図:

Dexamethasone 3 mg in 1 mL

投与経路:

INTRAVENOUS

処方タイプ:

PRESCRIPTION

適応症:

INDICATIONS AND USAGE: Dexamethasone-SP (dexamethasone sodium phosphate) is indicated as a rapid adrenal glucocorticoid and/or anti-inflammatory agent in horses. Do not use in viral infections. Except when used for emergency therapy, dexamethasone sodium phosphate is contraindicated in animals with tuberculosis and chronic nephritis. Existence of congestive heart failure, osteoporosis and diabetes are relative contraindications. In the presence of infection appropriate antibacterial agents should also be administered and should be continued for at least 3 days after discontinuance of the hormone and disappearance of all signs of infection.

製品概要:

HOW SUPPLIED: Dexamethasone-SP (dexamethasone sodium phosphate) 4 mg/mL (equivalent to 3 mg/mL dexamethasone) is available in 100 mL multiple dose vials.

認証ステータス:

Abbreviated New Animal Drug Application

製品の特徴

DEXAMETHASONE SP- DEXAMETHASONE SODIUM PHOSPHATE INJECTION, SOLUTION
MWI/VETONE
----------
DEXAMETHASONE-SP
(DEXAMETHASONE SODIUM PHOSPHATE)
INJECTION USP FOR HORSES
4 MG/ML
EQUIVALENT TO DEXAMETHASONE 3 MG/ML
FOR INTRAVENOUS USE IN HORSES ONLY
NOT FOR USE IN HUMANS
KEEP OUT OF REACH OF CHILDREN
WARNING: DO NOT USE IN HORSES INTENDED FOR FOOD
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION:
Dexamethasone sodium phosphate (a synthetic adrenocortical steroid),
is a white or
slightly yellow crystalline powder. It is freely soluble in water and
is exceedingly
hygroscopic.
Each mL of Dexamethasone-SP (dexamethasone sodium phosphate) contains
Dexamethasone Sodium Phosphate 4 mg (equivalent to dexamethasone 3
mg), Sodium
Citrate 10 mg, Sodium Bisulfite 2 mg, Benzyl Alcohol 1.5% as a
preservative, in Water
for Injection q.s. Sodium Hydroxide and/or Hydrochloric Acid to adjust
pH to between
7.0 and 8.5.
CLINICAL PHARMACOLOGY:
Dexamethasone is a synthetic corticosteroid and possesses
glucocorticoid activity.
Dexamethasone sodium phosphate is a salt of dexamethasone that is
particularly
suitable for intravenous administration because it is highly water
soluble, permitting
administration of relatively large doses in a small volume of diluent.
Dexamethasone, as a steroid, is equivalent in potency to some
established steroids while
being considerably more potent than others. In the case of the dog,
dexamethasone is
found to be about equivalent in dosage to prednisone but about 30 to
40 times more
potent than prednisolone.
INDICATIONS AND USAGE:
Dexamethasone-SP (dexamethasone sodium phosphate) is indicated as a
rapid adrenal
glucocorticoid and/or anti-inflammatory agent in horses.
Do not use in viral infections. Except when used for emergency
therapy,
dexamethasone sodium phosphate is contraindicated in animals with
tuberculosis and
chronic nephritis. Existence of congestive heart failure, osteoporosis
and diabetes are
relative contraindications.
In the presence of inf