国: シンガポール
言語: 英語
ソース: HSA (Health Sciences Authority)
Verapamil Hydrochloride
ABBOTT LABORATORIES (SINGAPORE ) PRIVATE LIMITED
C08DA01
240 mg
TABLET, FILM COATED
Verapamil Hydrochloride 240.0 mg
ORAL
Prescription Only
AbbVie Deutschland GmbH & Co. Kg
ACTIVE
1988-04-22
CCDS1000326220 Updated: 12/2/2014 ISOPTIN ® SR 240MG ACTIVE DRUG SUBSTANCE: VERAPAMIL HYDROCHLORIDE FILM COATED TABLETS WITH PROLONGED ACTION CALCIUM ANTAGONIST FOR THE TREATMENT OF HYPERTENSION QUALITATIVE AND QUANTITATIVE COMPOSITION Verapamil hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). The chemical name of verapamil hydrochloride is benzeneacetonitrile, α-[3-[{2-(3, 4-dimethoxyphenyl) ethyl} methylamino] propyl]-3,4-dimethoxy-α-(1-methylethyl) hydrochloride. It has a molecular weight of 491.07 and the molecular formula is C27H38N204•HCl. COMPOSITION 1 film coated tablet contains 240mg of verapamil hydrochloride. PHARMACEUTICAL FORM Verapamil hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). Verapamil hydrochloride is an almost white, crystalline powder, practically free of odor, with a bitter taste. It is soluble in water, freely soluble in chloroform, sparingly soluble in alcohol and practically insoluble in ether. CLINICAL PARTICULARS THERAPEUTIC INDICATIONS Hypertension POSOLOGY AND METHOD OF ADMINISTRATION The doses of Isoptin SR 240mg, individualized according to the severity of the disease, are to be taken regularly as prescribed by the physician. The film coated tablets are to be swallowed whole with some fluid, preferably with or shortly after meals. Unless otherwise instructed, the daily dose for adults is 1 film coated tablet in the morning (patients requiring particularly gradual blood pressure lowering should be started on half tablet taken in the morning). If after about 2 weeks of treatment a dose increase is found to be necessary the dose can be raised to a maximum of 2 film coated tablets daily (additionally 1 half to 1 film coated tablet in 完全なドキュメントを読む
RDCCDS000462/13 Updated: 15-Oct-20 ISOPTIN ® SR 240MG ACTIVE DRUG SUBSTANCE: VERAPAMIL HYDROCHLORIDE FILM COATED TABLETS WITH PROLONGED ACTION CALCIUM ANTAGONIST FOR THE TREATMENT OF HYPERTENSION QUALITATIVE AND QUANTITATIVE COMPOSITION Verapamil hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). The chemical name of verapamil hydrochloride is benzeneacetonitrile, α-[3-[{2-(3, 4-dimethoxyphenyl) ethyl} methylamino] propyl]-3,4-dimethoxy-α-(1-methylethyl) hydrochloride. It has a molecular weight of 491.07 and the molecular formula is C27H38N204•HCl. COMPOSITION 1 film coated tablet contains 240mg of verapamil hydrochloride. PHARMACEUTICAL FORM Verapamil hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). Verapamil hydrochloride is an almost white, crystalline powder, practically free of odor, with a bitter taste. It is soluble in water, freely soluble in chloroform, sparingly soluble in alcohol and practically insoluble in ether. CLINICAL PARTICULARS THERAPEUTIC INDICATIONS Hypertension POSOLOGY AND METHOD OF ADMINISTRATION The doses of Isoptin ® SR 240mg, individualized according to the severity of the disease, are to be taken regularly as prescribed by the physician. The film coated tablets are to be swallowed whole with some fluid, preferably with or shortly after meals. Unless otherwise instructed, the daily dose for adults is 1 film coated tablet in the morning (patients requiring particularly gradual blood pressure lowering should be started on half tablet taken in the morning). If after about 2 weeks of treatment a dose increase is found to be necessary the dose can be raised to a maximum of 2 film coated tablets daily (additionally 1 half to 1 film coated tablet in the evening after an interval of about 12 hours). On long-term treatment a daily dose of 480mg should not be exceeded; short-term dose increases are possible only when directed by the physician. For children and adults requiring smaller doses 完全なドキュメントを読む