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1209 CYPROSTAT
®
CMI
Page 1 of 5
CYPROSTAT
®
(SIGH·PRO·STAT)
_ _
_cyproterone acetate _
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS
LEAFLET
This leaflet answers some
common questions about
Cyprostat.
It does not contain all the
available information. It does not
take the place of talking to your
doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has
weighed the risks of you taking
Cyprostat against the benefits
they expect it will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE
MEDICINE.
You may need to read it again.
WHAT CYPROSTAT IS
USED FOR
Cyprostat is an anti-androgen
medicine.
Androgens such as testosterone
are natural male sex hormones
which are also produced, to a
slight extent, in females.
MEN:
In men, androgens may help
cancer cells to grow in some
types of prostate cancer. By
blocking these hormones,
Cyprostat may slow or stop the
growth of cancer. Cyprostat may
also be used in combination with
other medicines or following
surgical removal of the testes to
treat side effects such as “hot
flushes” or “sweats” and to
prevent any initial worsening of
the disease.
Cyprostat is also used to reduce
abnormal sex drive in men.
WOMEN:
In women, androgens may
increase hair growth, loss of scalp
hair and secretion of oil from the
sweat glands. By blocking these
hormones, Cyprostat may slow or
stop excessive hairiness, loss of
scalp hair, acne, oily skin and
dandruff.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS
MEDICINE HAS BEEN PRESCRIBED
FOR YOU.
Your doctor may have prescribed
it for another reason.
This medicine is available only
with a do
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제품 특성 요약
CYPROSTAT
®
50MG PRODUCT INFORMATION
NAME OF THE MEDICINE
Cyprostat 50mg
Each pack contains tablets with 50mg cyproterone acetate.
Cyproterone acetate:
CH
3
CH
3
H
H
H
O
O
CH
3
O
Cl
O
Chemical Name:
6-chloro-17
α hydroxy-1α,2α-methylene-pregna-4,6-diene-3,20-dione
actetate
Molecular Formula:
C
24
H
29
CIO
4
Molecular Mass:
416.96
CAS No.:
427-51-0
DESCRIPTION
Cyproterone acetate is a white to pale yellow crystalline powder.
M.P. 206-213
°C.
Cyproterone acetate is very soluble in chloroform and
dioxane, freely soluble in acetone and
benzene, soluble in ethanol, methanol and ethyl acetate, sparingly
soluble in solvent
hexane, and almost insoluble in water.
PHARMACOLOGY
Cyprostat 50mg is an antiandrogenic hormone preparation.
Cyproterone acetate inhibits competitively the effect
of androgens at androgen-dependent
target organs, e.g. it shields the prostate from the effect of
androgens originating from the
gonads and/or the adrenal cortex. Prostatic carcinoma and its
metastases are in general
androgen-dependent, cyproterone acetate therefore exerts a direct
antiandrogenic action on
the tumour and its metastases.
Cyproterone acetate in addition has a progestogenic action exerting a
negative feedback
effect centrally on the hypothalamic receptors, so leading to a
reduction in gonadotropin
release, and hence to diminished production of
testicular androgens. Treatment with
cyproterone acetate in men results in a reduction of sexual drive
and potency and inhibition
of gonadal function. These changes are reversible following
discontinuation of the therapy.
The antigonadotropic effect of cyproterone acetate is
also exerted when the substance is
combined with LHRH agonists. The initial increase of testosterone
provoked by this
substance group is decreased by cyproterone acetate.
101109 CYPROSTAT 50mg PI
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