Šalis: Malaizija
kalba: anglų
Šaltinis: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Diosmin; Hesperidin
PERNIAGAAN NORMAHAS SDN. BHD.
Diosmin; Hesperidin
30 Tablets
Saga Lifesciences Limited
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ 1 VEINOSMIN FILM COATED TABLETS Diosmin/Hesperidin (450mg/50mg) WHAT IS IN THIS LEAFLET 1. What Veinosmin is used for 2. How Veinosmin works 3. Before you use Veinosmin 4. How to use Veinosmin 5. While you are using it 6. Side effects 7. Storage and disposal of Veinosmin 8. Product description 9. Manufacturer and product registration holder 10. Date of revision WHAT VEINOSMIN IS USED FOR It is recommended for the treatment for venous circulation disorders (heavy legs, pain, early morning restless legs) and the treatment of symptoms related to hemorrhoids (acute hemorrhoidal attack). HOW VEINOSMIN WORKS This medicine strengthens veins by increasing venous tone, and protects small blood vessels. BEFORE YOU USE VEINOSMIN _When you must not use it_ DO NOT TAKE VEINOSMIN FILM-COATED TABLET: If you are allergic (hypersensitive) to diosmin, hesperidin, micronized purified flavonoid fraction or any of the other ingredients of this medicine (see Ingredients section). Do not use in children below 18 years old unless advised by your doctor. _Before you start to use it_ Ask your doctor or pharmacist for advice before taking this medicine. PREGNANCY AND BREAST-FEEDING: If you are pregnant, think you may be pregnant, planning to have a baby, or breast-feeding, ask your doctor or pharmacist for advice before taking this medicine. _Taking other medicines_ Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. HOW TO USE VEINOSMIN Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. _How much to use & When to use it_ _VENOUS CIRCULATION DISORDERS_ The recommended dose is 2 tablets daily; i.e. one at midday and one in the evening at mealtimes. _ACUTE HEMORRHOIDAL ATTACK_ The recommended dose is 6 tablets daily for 4 days, then 4 tablets daily for the next 3 days at mealtimes. _How long to use Perskaitykite visą dokumentą
1. PRODUCT NAME: VEINOSMIN Film Coated Tablets 2. QUALITATIVE AND QUANTITATIVE COMPOSITION: Each film-coated tablet contains: Diosmin 450mg and Hesperidin 50mg Excipients: Microcrystalline cellulose powder, maize starch, colloidal anhydrous silica, povidone K 30, sodium lauryl sulphate, citric acid, purified water, magnesium stearate, purified talc, croscarmellose sodium, titanium dioxide, yellow iron oxide, red iron oxide 3. DOSAGE FORM: Film-coated tablet 4. PRODUCT DESCRIPTION: Peach colored oval shaped film coated tablet having break line on one side. 5. PHARMACODYNAMICS: In pharmacology: VEINOSMIN exerts an action on the vascular return system: - at the venous level, it reduces venous distensibility and reduces venous stasis; - at the microcirculatory level, it normalises capillary permeability and reinforces capillary resistance. In clinical pharmacology: Controlled, double-blind studies using methods that allow demonstrating and quantifying the activity on venous haemodynamics have confirmed the pharmacological properties of this medicinal product in humans. - dose/effect relationship: Statistically-significant dose-effect relationships have been demonstrated for the following venous plethysmography parameters: capacitance, distensibility and emptying time. The best dose/effect ratio is obtained with 2 tablets. - venotonic activity: It increases venous tone: venous occlusion plethysmography with a mercury strain gauge revealed a reduction in venous emptying time. - microcirculatory activity: Controlled, double-blind studies have demonstrated a statistically-significant difference between this medicinal product and placebo. In patients with signs of capillary fragility, it increases capillary resistance as measured by angiosterrometry. 6. PHARMACOKINETICS: In humans, following oral administration of the medicinal product with carbon 14-labelled diosmin: - Excretion is essentially faecal and urinary excretion is on average 14% of the administered quantity, - The elimination half-life is 11 hours, - The produ Perskaitykite visą dokumentą