ACTIHIST SYRUP

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PSEUDOEPHEDRINE HYDROCHLORIDE; TRIPROLIDINE HYDROCHLORIDE

Boleh didapati daripada:

HOVID BERHAD

INN (Nama Antarabangsa):

PSEUDOEPHEDRINE HYDROCHLORIDE; TRIPROLIDINE HYDROCHLORIDE

Unit dalam pakej:

60 ml; 100 ml; 120 ml; 3600 ml; 120 ml

Dikeluarkan oleh:

HOVID BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
ACTIHIST SYRUP
Triprolidone hydrochloride/Pseudoephedrine hydrochloride (1.25mg/30mg
per 5ml)
1
WHAT IS IN THIS LEAFLET
1.
What Actihist Syrup is used for
2.
How Actihist Syrup works
3.
Before you use Actihist Syrup
4.
How to use Actihist Syrup
5.
While you are using Actihist Syrup
6.
Side effects
7.
Storage
and
disposal
of
Actihist
Syrup
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT ACTIHIST SYRUP
IS USED FOR
It
is
used
to
relieve
nasal
and
sinus
congestion
due
to
common
cold
and
allergic
rhinitis
(inflammation
of
the
mucous membrane inside the nose).
HOW ACTIHIST SYRUP
WORKS
This
medicine
contains
two
active
ingredients:
•
Pseudoephedrine hydrochloride, is
a
decongestant.
It
works
by
narrowing the blood vessels on the
nasal passages to decrease swelling
and congestion.
•
Triprolidine
hydrochloride,
an
antihistamine, that blocks the action
of histamine, hence helps to stop
sneezing and runny nose.
BEFORE YOU USE ACTIHIST SYRUP
_ _
_- When you must not use it _
Do not take this medicine if:
•
You
are
allergic
to
triprolidone
hydrochloride,
pseudoephedrine
hydrochloride
or
any
other
ingredients
(listed
in
Product
Description).
Do not use/give this medicine to:
•
premature babies or newborn
•
individuals
that
are
taking
anesthesia
•
individuals with overactive thyroid,
heart
disease
or
acute
asthma
attacks
•
individuals
on
anti-depressant
medicine
(monoamine
oxidase
inhibitors)
If you are not sure whether you should
start taking this medicine, talk to your
pharmacist or doctor.
_- Before you start to use it _
Tell your doctor/pharmacist if:
•
You have any allergies and elderly
individuals should use the medicine
with caution.
•
You have diabetes or high blood
pressure.
•
You have diabetes.
•
You
have
glaucoma
(increased
pressure in the eye).
•
You have kidney problem.
•
You have ulcer in digestive tract or
stomach.
Not to be used in children less than 2
years of age. To be used with cautio

Ciri produk

VIACT09-var (MY)3
ACTIHIST
DESCRIPTION
ACTIHIST SYRUP
Yellow transparent liquid with plum flavour.
ACTIHIST TABLET
Round, white uncoated tablet with shallow convex faces,
scored and "HD" embossed on the same face.
COMPOSITION
ACTIHIST SYRUP: Each 5 ml contains:
Triprolidine Hydrochloride
1.25 mg
Pseudoephedrine Hydrochloride
30.00 mg
ACTIHIST TABLET: Each tablet contains:
Triprolidine Hydrochloride
2.50 mg
Pseudoephedrine Hydrochloride
60.00 mg
PHARMACODYNAMICS
Pseudoephedrine is a sympathomimetic agent. It is used as a
bronchodilator and peripheral vasoconstrictor in preparations for
the relief of nasal and bronchial congestion. It has a stimulant
action on the respiratory center. It acts on alpha-adrenergic
receptors in the mucosa of the respiratory tract.
Triprolidine is an antihistamine. It is an antagonist of the H 1
receptor effects of histamine. It acts by competing with
histamine
for
H-1
receptor
sites
on
effector
cells.
It
diminishes or abolishes most of the actions of histamine
mediated by the H-1 receptors. The action of histamine most
readily affected is that on the involuntary muscle of the
intestines, bladder, uterus and bronchioles.
The antimuscarinic actions of Triprolidine provide a drying
effects on the nasal mucosa.
PHARMACOKINETICS
ABSORPTION: Well absorbed from the gastrointestinal tract.
METABOLIC REACTIONS: Both Pseudoephedrine and Triprolidine
are metabolized in the liver.
EXCRETION: Undergoes renal excretion. Pseudoephedrine is
largely excreted unchanged in the urine together with small
amounts of its hepatic metabolite while Triprolidine is mainly
excreted as metabolites in the urine. Both Pseudoephedrine
and Triprolidine are also excreted in breast milk.
INDICATIONS
This medication is used for the symptomatic relief of nasal
and sinus congestion associated with common cold and
allergic rhinitis.
CONTRAINDICATIONS
This medication should not be given to premature infants or
neonates,
patients
undergoing
anaesthesia
with
cyclopropane, halothane or other halogenated anaesthetics
and patient