GANFORT EYE DROPS

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

BIMATOPROST; TIMOLOL MALEATE

Boleh didapati daripada:

Allergan Malaysia Sdn Bhd

INN (Nama Antarabangsa):

BIMATOPROST; TIMOLOL MALEATE

Unit dalam pakej:

3ml mL

Dikeluarkan oleh:

ALLERGAN PHARMACEUTICALS IRELAND

Risalah maklumat

GANFORT
®
EYE DROPS
Bimatoprost/timolol
(0.3mg/5.0mg per ml)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What
GANFORT
®
is used for
2.
How
GANFORT
®
works
3.
Before you use
GANFORT
®
4.
How to use
GANFORT
®
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
GANFORT
®
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT GANFORT
® IS USED FOR
GANFORT
®
is prescribed to lower the
pressure
in
the
eye
of
people
with
glaucoma
or
high
pressure
in
the
eye
when other medicines like beta blockers
or
prostaglandin
analogues
used
alone
are not enough.
HOW GANFORT
® WORKS
GANFORT
®
works
by
reducing
the
production of liquid and also increasing
the amount of liquid that is drained. This
reduces the pressure inside the eye.
BEFORE YOU USE GANFORT
®
-
_When you must not use it_
_ _
_ _
Do not use
GANFORT
®
:
-
if you are allergic (hypersensitive to
bimatoprost or timolol, or any of the
other
ingredients
of
GANFORT
®
.
(for
a
full
list
of
ingredients,
see
section
“PRODUCT
DESCRIPTION”).
-
if you have now or have had in the
past
respiratory
problems
such
as
asthma,
severe
chronic
obstructive
lung disease.
-
if you have heart problems such as
low heart rate, heart failure, heart
beat disorders (unless controlled by
a pacemaker).
-
_Pregnancy and lactation _
If you are pregnant or breast-feeding,
think
you
may
be
pregnant
or
are
planning
to
have
a
baby,
ask
your
doctor or pharmacist for advice before
taking
this
medicine.
Do
not
use
GANFORT
®
if
you
are
pregnant
unless your doctor still recommends it.
Do not use
GANFORT
®
if you are
breast-feeding. Timolol may get into
your breast milk. Ask your doctor for
advice
before
taking
any
medicine
during breast-feeding.
-
_Children and adolescents_
_ _
GANFORT
®
has only been studied in
adults
and
therefore
its
use
is
not
recommended
in
children
or
adolescents.
-
_Before you start to use it _
Take special care with
GANFORT
®
.
Always use
GANFORT
®
exactly as
your doctor or

Ciri produk

GAN FO RT® e ye d ro p s, s o lu tio n
B imat op ro st 0 .3 m g/mL a n d t im olo l 5 .0 m g/mL
DESC R IP T IO N
Each mL c o n ta in s: 0 .3 mg b imat op ro st a n d 5 mg t im olo l e q u iv a le n t t o 6.8 mg o f t im olo l
mal eat e, b en za lk o n iu m ch lo rid e as p re se rv a tiv e, s o d iu m ch lo rid e, d ib asic s o d iu m p hosph ate
h ep ta h yd ra te, c it ric ac id m on oh yd ra te, h yd ro ch lo ric a cid or so d iu m h yd ro xid e ( t o a d ju st pH ),
pu rif ied w ate r.
CLIN IC AL
P H AR M ACO LO GY
Pharma co d yn amic p ro p ertie s
P harm aco th era peu tic g ro up:
O ph th alm olo gic a l – b eta -b lo ck in g a ge n ts – t im olo l, co m bin atio n s
A TC c o d e: SO 1ED 5 1
M ech anism o f a ctio n :
G AN FO RT® c o nsis ts o f two ac tiv e s ubs ta nc es: b imat op ro st a n d t im olo l ma le at e. T h ese tw o
c o m pon en ts d ecre ase e le va ted i n tra o cu la r p re ss ure ( IOP) b y c o m ple m en ta ry mec han is ms o f
ac tio n a n d t h e c o m bin ed ef fect r e su lt s in a d d it ion al IOP r e d u ctio n c o m pared t o e it h er
c o m pou nd a d m in is te red a lo ne. G AN FO RT® h as a r a p id o n set o f ac tio n.
B imat op ro st i s a p ote n t o cu lar hyp ote n siv e a ge n t. I t is a sy nth etic p ro stam id e, s tr uc tu ra lly
r e la ted t o pro sta gla n d in F 2
α (P G F2 α) t h at ac ts t h ro ugh an i d en tif ied p ro stam id e r ece pto r. T h e
mec han is m o f ac tio n b y w hic h b imat op ro st r e d u ces i n tra o cu lar pre ss ure in man is by inc re asin g
a qu eou s hu mour o u tflo w t h ro ugh t h e t ra b ec ular me sh w or k a n d e nh anc in g uve o sc le ral ou tflo w.
Ti m olo l is a b eta 1 an d b eta 2 n on -s e lec tiv e a d re n erg ic r ece pto r b lo ck in g a ge n t t h at d oes n o t have
s ig n if ic a n t in tr in sic sy mpath om ime tic , d ir ect m yo ca rd ia l d ep re ssa nt, o r lo cal an ae sth etic
( me mbra n e‑s ta b il is in g) ac tiv it y . Ti m olol lo wers I O P b y r e du cin g a qu eou s hu mou r f o rma