Country: Afrika Selatan
Bahasa: Inggeris
Sumber: South African Health Products Regulatory Authority (SAHPRA)
Lennon
PETHIDINE INJECTION INTRAMED 25 mg/mL PETHIDINE INJECTION INTRAMED 50 mg/mL PETHIDINE INJECTION INTRAMED 100 mg/2 mL SCHEDULING STATUS: S7 PROPRIETARY NAME (and dosage form): PETHIDINE INJECTION INTRAMED 25 mg/mL PETHIDINE INJECTION INTRAMED 50 mg/mL PETHIDINE INJECTION INTRAMED 100 mg/2 mL COMPOSITION: 1 mL Ampoules containing 25 mg Pethidine Hydrochloride. 1 mL Ampoules containing 50 mg Pethidine Hydrochloride. 2 mL Ampoules containing 100 mg Pethidine Hydrochloride. PHARMACOLOGICAL CLASSIFICATION: A 2.9 Other Analgesics PHARMACOLOGICAL ACTION: Pethidine has an analgesic potency approximately equal to one-fifth that of morphine. Pethidine binds to the opioid receptors in the central nervous system and exerts it’s main pharmacological action on the central nervous system and the neural elements of the bowel. INDICATIONS: Pethidine is indicated for the relief of pain. It is particularly useful for the relief of post-operative pain. It may be used in obstetric practice to relieve labour pain. CONTRA-INDICATIONS: Pethidine is contra-indicated in respiratory depression, obstructive pulmonary disease, hepatic insufficiency and pain following cholecystectomy and for the relief of pain associated with renal colic. Increased intracranial pressure is also a contra-indication. It must not be administered to patients receiving phenothiazines or meprobamates. Pethidine should not be given to patients who are being treated with monoamine oxidase inhibitors, or within 2 weeks of the discontinuation of such treatment. WARNING: Dependence can occur. DOSAGE AND DIRECTIONS FOR USE: Children: 1 to 1,5 mg per kg body-mass given intramuscular or subcutaneous, but not exceeding the adult dose. Adults: 50 to 100 mg S.C., I.M. or in reduced doses I.V. repeated every 3 to 4 hours if required but not exceedin Baca dokumen lengkap