PROPERAZINE TABLET 5MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PROCHLORPERAZINE MALEATE

Boleh didapati daripada:

SUNWARD PHARMACEUTICAL SDN. BHD.

INN (Nama Antarabangsa):

PROCHLORPERAZINE MALEATE

Unit dalam pakej:

10x10 Tablets; 100x10 Tablets; 50x10 Tablets; 1000 Tablets

Dikeluarkan oleh:

SUNWARD PHARM PTE LTD

Risalah maklumat

PROPERAZINE TABLET
Prochlorperazine Maleate (5mg)
1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET
1. What Properazine Tablet is used for
2. How Properazine Tablet works
3. Before you use Properazine Tablet
4. How to Use Properazine Tablet
5. While you are using it
6. Side effects
7. Storage and disposal of Properazine Tablet
8. Product description
9. Manufacturer and Product Registration
Holder
10. Date of revision
WHAT PROPERAZINE TABLET IS USED FOR
Properazine
Tablet
is
used
for
control
of
severe nausea and vomiting and treatment of
non-psychotic anxiety.
HOW PROPERAZINE TABLET WORKS
The active
ingredient
in the medicine is
prochlorperazine
maleate. Prochlorperazine
maleate
works
by
correcting
chemical
imbalances in the brain that causes nausea,
vomiting and anxiety.
BEFORE YOU USE PROPERAZINE TABLET
_- When you must not use it _
Do not take this medicine if you:

are
hypersensitive
to
prochlorperazine
maleate, or any other ingredients of this
medicine (listed in Product Description).

have bone marrow depression.

have depression
Do not use for children under 2 years of age
or under 9kg in weight as safety has not been
established.
_- Before you start to use it _
Tell your doctor if you have:

Reye's syndrome and other illness affecting
the brain.

glaucoma (increased pressure in eyes).

exposed to extreme heat.

surgery recently.

intestinal obstruction.
_Pregnancy and lactation _
Please consult your doctor or pharmacist if
you are pregnant, planning for pregnancy or
breast-feeding before using any medicine.
Do not take this medicine if you are pregnant
or
breastfeeding
as
the
medicine
may
be
secreted into the breast milk and cause side
effects in infants.
Side
effects
such
as
jaundice,
agitation,
muscle spasm, tremor seen in new born whose
mothers received prochlorperazine maleate.
_- Taking other medicines _
Tell your doctor if you are taking:-

medicine for cancer treatment.

blood thinning agent.

medicines to treat high blood pressure called
t

Ciri produk

Because phenothiazines may interfere with thermoregulatory mechanisms,
use with caution in persons who will be exposed to
extreme heat.
Phenothiazines can produce alpha-adrenergic blockade.
The presence of phenothiazines may produce false-positive
phenylketonuria (PKU) test results.
DRUG INTERACTIONS:
When prochlorperazine is used with cancer chemotherapeutic drugs,
vomiting as a sign of the toxicity of these agents may be
obscured by the antiemetic effect of prochlorperazine.
Phenothiazines can diminish the effect of oral anticoagulants.
Thiazide diuretics may accentuate the orthostatic hypotension that may
occur with phenothiazines. Antihypertensive effects of
guanethidine and related compounds may be counteracted when
phenothiazines are used concomitantly.
Concomitant administration of propranolol with phenothiazines results
in increased plasma levels of both drugs.
USE IN PREGNANCY AND LACTATION:
Safety for the use of prochlorperazine during pregnancy has not been
established. Therefore, prochlorperazine is not
recommended for use in pregnant patients except in cases of severe
nausea and vomiting that are so serious and intractable
that, in the judgement of the physician, drug intervention is required
and potential benefits outweigh possible hazards.
There have been reported instances of prolonged jaundice,
extrapyramidal signs, hyperreflexia or hyporeflexia in new born
infants whose mothers received phenothiazines.
There is evidence that phenothiazines are excreted in the breast milk
of nursing mothers. Caution should be exercised when
prochlorperazine is administered to a nursing woman.
DOSAGE:
Route of administration - Oral
Adults: Dosage should be tailored to the individual response,
carefully monitored, and dosage adjusted accordingly. Dosage
should be increased more gradually in elderly patients.
To control severe nausea and vomiting: 5 mg or 10 mg 3 or 4 times
daily.
Non-psychotic anxiety: 5 mg or 10 mg 3 or 4 times daily.
Children: Children seem more prone to develop extrapyramidal
reactions, even on