Pajjiż: Singapor
Lingwa: Ingliż
Sors: HSA (Health Sciences Authority)
ACETYLSALICYLIC ACID
BAYER (SOUTH EAST ASIA) PTE LTD
N02BA01
500 mg
TABLET
ACETYLSALICYLIC ACID 500 mg
ORAL
General Sale List
PT Bayer Indonesia
ACTIVE
1991-01-29
- Hypersensitivity to acetylsalicylic acid, other salicylates or any of the excipients as listed in the composition. - History of bronchospasm, urticaria or allergy-like symptoms after taking acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs. - Active stomach and/or duodenal ulcers or gastrointestinal bleeding. - Inflammatory bowel disease (e.g. Crohn's disease or ulcerative colitis). - Haemorrhagic diathesis. - Severe hepatic impairment (liver cirrhosis and ascites). - Severe renal impairment (creatinine clearance < 30 ml/min). - Severe heart failure (NYHA III-IV). - Combination with methotrexate at doses of 15 mg/week or more (see "Interactions"). - Treatment of post-operative pain following a coronary artery bypass graft (or use of a heart-lung machine). - Last trimester of pregnancy (see "Pregnancy and Lactation"). WARNINGS AND PRECAUTIONS Risk of GI Ulceration, Bleeding and Perforation with NSAID Serious GI toxicity such as bleeding, ulceration and perforation can occur at any time, with or without warning symptoms, in patients treated with NSAID therapy. Although minor upper GI problems (e.g. dyspepsia) are common, usually developing early in therapy, prescribers should remain alert for ulceration and bleeding in patients treated with NSAIDs even in the absence of previous GI tract symptoms. Studies to date have not identified any subset of patients not at risk of developing peptic ulceration and bleeding. Patients with prior history of serious GI events and other risk factors associated with peptic ulcer disease (e.g. alcoholism, smoking, and corticosteroid therapy) are at increased risk. Elderly or debilitated patients seem to tolerate ulceration or bleeding less than other individuals and account for most spontaneous reports for fatal GI events. The renal effects of NSAIDs include fluid retention with oedema and/or arterial hypertension. Therefore, acetylsalicylic acid should only be used with caution in patients with impaired cardiac function and other predisposing conditions for fluid Aqra d-dokument sħiħ