Land: Singapore
Språk: engelsk
Kilde: HSA (Health Sciences Authority)
Vancomycin Hydrochloride 512.571mg/vial equivalent to Vancomycin
MYLAN PHARMACEUTICALS PTE. LTD.
J01XA01
500 mg
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Vancomycin Hydrochloride 512.571mg/vial equivalent to Vancomycin 500 mg
INTRAVENOUS
Prescription Only
Mylan Laboratories Limited - Specialty Formulation Facility
ACTIVE
2009-12-14
DHACOCIN - Vancomycin Hydrochloride for Injection 500 mg/vial 300 x 290 mm Ver. 7; Date: 18.03.2021 Mylan / Singapore Pack Insert -- 1 Black = For Position Only. Codes shall be assigned during commercial artwork preparation. FRONT SIDE PRODUCT DESCRIPTION: Vancomycin Hydrochloride for Injection is a white to off white lyophilized plug or powder filled in glass vial. May contain hydrochloric acid and/or sodium hydroxide for pH adjustment. When reconstituted with Sterile Water for Injection, USP, it forms a clear solution. This product is oxygen sensitive. Solutions of vancomycin hydrochloride reconstituted with Sterile Water for Injection contain no bacteriostat and are intended for use only as a single-dose injection. When smaller doses are required, the unused portion should be discarded. When reconstituted with sterile water for injection, further dilution is required before use. COMPOSITION: Each vial contains: Vancomycin Hydrochloride (lyophilized) equivalent to Vancomycin 500 mg. PHARMACOLOGY: Vancomycin is a tricyclic glycopeptide antibiotic derived from Amycolatopsis orientalis (formerly Nocardia orientalis) and has the molecular formula C 66 H 75 C l2 N 9 O 24 • HCl. The molecular weight is 1485.74; 500 mg of the base is equivalent to 0.34 mmol. Vancomycin has bactericidal action against a variety of Gram-positive bacteria. It is not active in- vitro against gram-negative bacilli, mycobacteria or fungi. It exerts its action by inhibiting cell wall biosynthesis of susceptible bacteria. There is also evidence that Vancomycin alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis. There is no cross- resistance between Vancomycin and other antibiotics. Microbiology - The bactericidal action of vancomycin results primarily from inhibition of cell-wall biosynthesis. In addition, vancomycin alters bacterial-cell-membrane permeability and RNA synthesis. There is no cross- resistance between vancomycin and other antibiotics. Vancomycin is not active in vitro against gram read_full_document