Land: Canada
Taal: Engels
Bron: Health Canada
CEFOTAXIME SODIUM
SANOFI-AVENTIS CANADA INC
J01DD01
CEFOTAXIME
2G
POWDER FOR SOLUTION
CEFOTAXIME SODIUM 2G
INTRAMUSCULAR
IM:6ML/IV:11ML/IV INF.:56ML TO 1011ML; 10X2G
Prescription
THIRD GENERATION CEPHALOSPORINS
Active ingredient group (AIG) number: 0152507002; AHFS:
CANCELLED POST MARKET
2017-11-24
PRODUCT MONOGRAPH PR CLAFORAN ® Cefotaxime for injection, Mfr. Std. 1g and 2g cefotaxime (as cefotaxime sodium) per vial β-lactam Antibiotic sanofi-aventis Canada Inc. 2905 Place Louis-R-Renaud Laval, Quebec H7V 0A3 Date of Revision: November 12, 2014 Submission Control No.: 176886 s-a Version dated 2 PRODUCT MONOGRAPH PR CLAFORAN ® Cefotaxime for injection, Mfr. Std. 1g and 2g cefotaxime (as cefotaxime sodium) per vial β-lactam Antibiotic ACTION AND CLINICAL PHARMACOLOGY CLAFORAN (cefotaxime for injection) is a semi-synthetic, 2-aminothiazolyl cephalosporin antibiotic for parenteral use. _In vitro _studies indicate that the antibacterial action of CLAFORAN results from inhibition of cell wall synthesis. It is stable against the action of most β-lactamases. INDICATIONS AND CLINICAL USE TREATMENT _ _ _ _ CLAFORAN (cefotaxime for injection) may be indicated for the treatment of infections caused by susceptible strains of the designated micro-organisms in the diseases listed below. LOWER RESPIRATORY TRACT INFECTIONS: Pneumonia and lung abscess caused by _Streptococcus _ _pneumoniae_ (formerly _Diplococcus_ _pneumoniae_), other streptococci (excluding enterococci, e.g. _S. faecalis_),_ Staphylococcus_ _aureus_ (penicillinase and non-penicillinase producing),_ _ _Escherichia _ _coli_,_ _ _Hemophilus _ _influenzae_, (including ampicillin resistant strains) and unspecified _Klebsiella_ species. URINARY TRACT INFECTIONS: Caused by _Escherichia coli_, unspecified _Klebsiella_ species (including _K. pneumoniae_),_ Proteus_ _mirabilis_, indole positive _ Proteus_, _ Serratia marcescens_ and _ Staphylococcus epidermidis_. Also, uncomplicated gonorrhea caused by _N. gonorrhoeae_ including penicillin resistant strains. BACTEREMIA/SEPTICEMIA: Caused by _Escherichia coli_, unspecified _Klebsiella_ strains and _Serratia marcescens_. SKIN INFECTIONS: Caused by _Staphylococcus _ _aureus_ (penicillinase and non-penicillinase producing), _S. epidermidis_, group A streptococci, _ Escherichia coli_, _ Proteus mirabilis_ and indole Lees het volledige document