Kraj: Australia
Język: angielski
Źródło: Department of Health (Therapeutic Goods Administration)
venlafaxine hydrochloride
Amneal Pharma Australia Pty Ltd
Venlafaxine hydrochloride
Registered
________________________________________________________________________________ Venla/CMIAN 20170117 Page 1 of 6 VENLAFAXINE AN SR _Venlafaxine Hydrochloride Modified Release Capsules _ CONSUMER MEDICINE INFORMATION _ _ WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Venlafaxine AN SR modified release capsules. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist or asking questions. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Venlafaxine AN SR against the expected benefits it will have for you. IF YOU HAVE ANY QUESTIONS ABOUT VENLAFAXINE AN SR, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH YOUR VENLAFAXINE AN SR MODIFIED RELEASE CAPSULES. You may need to read it again. WHAT VENLAFAXINE AN SR IS FOR _WHAT IT DOES _ Venlafaxine AN SR modified release capsules are used in the treatment and prevention of relapse of depression and panic attacks and in the treatment of anxiety, including avoidance or fear of social situations. Depression can affect your whole body and may cause emotional and physical symptoms such as feeling low in spirit, being unable to enjoy life, poor appetite or overeating, disturbed sleep, loss of sex drive, lack of energy and feeling guilty over nothing. Excessive anxiety is a condition in which you feel constantly and uncontrollably worried and distressed. It may also make you feel irritable, and cause difficulty in thinking and sleeping. Other common symptoms associated with anxiety may include a dry mouth, a lump in the throat, cold clammy hands, diarrhoea and nausea. Depression and anxiety are treatable illnesses. Anxiety or tension associated with the normal stress of everyday life usually does not require treatment with medicines. _HOW IT WORKS _ Venlafaxine AN SR contains the active ingredient called venlafaxine hydrochloride. It belongs to a class of medications for depression and anxiety, called Serotonin- Noradrenaline Reuptake Inhibitors (SNRIs Przeczytaj cały dokument
PI Venlafaxine AN SR 20170808 Page 1 of 35 PRODUCT INFORMATION VENLAFAXINE AN SR (MODIFIED RELEASE CAPSULES) NAME OF THE MEDICINE PROPRIETARY NAME: Venlafaxine AN SR NON PROPRIETARY NAME: Venlafaxine (as hydrochloride) 37.5 mg, 75 mg and 150 mg modified release capsules. Its chemical structure is: CAS Number: 99300-78-4 DESCRIPTION Venlafaxine AN SR capsules are a modified release formulation, which release the active constituent, venlafaxine hydrochloride, from mini-tablets within the capsule. Drug release is controlled by diffusion through the coating on the mini-tablets and is not pH dependent. Three strengths of Venlafaxine AN SR capsules are available containing 37.5 mg, 75 mg or 150 mg of venlafaxine (as hydrochloride). The full chemical name for Venlafaxine hydrochloride is 1-[(R/S)-2-(2-dimethylamino)-1- (4-methoxyphenyl)ethyl]cyclohexanol hydrochloride. It is a white to off-white crystalline solid with a solubility of 572 mg/mL in water (adjusted to ionic strength of 0.2 M with sodium chloride). Its molecular weight is 313.9 and its molecular formula is C 17 H 27 NO 2 ,HCl. Other ingredients are microcrystalline cellulose, povidone, purified talc, colloidal anhydrous silica, magnesium stearate, ethylcellulose and copovidone. For each strength, the capsule shells contain: 37.5 mg: gelatin, titanium dioxide, iron oxide black, iron oxide red and iron oxide yellow. The printing uses TekPrint SB-1033 Red Ink. PI Venlafaxine AN SR 20170808 Page 2 of 35 75 mg: gelatin, titanium dioxide, iron oxide black and iron oxide red. The printing uses TekPrint SB-1033 Red Ink. 150 mg: gelatin, titanium dioxide, Brilliant Blue FCF, Allura Red AC and Sunset Yellow FCF. The printing uses TekPrint SB-0007P White Ink. PHARMACOLOGY _ACTIONS _ Venlafaxine is a structurally novel antidepressant for oral administration; it is chemically unrelated to tricyclic, tetracyclic, or other available antidepressant agents. _PHARMACODYNAMICS _ The antidepressant action of venlafaxine in humans is believed to be associated with its potentiat Przeczytaj cały dokument