País: Nova Zelândia
Língua: inglês
Origem: Ministry for Primary Industries
levothyroxine sodium pentahydrate
Schering-Plough Animal Health Limited
levothyroxine sodium pentahydrate
levothyroxine sodium pentahydrate 1 g/litre
Endocrine agent (hormone)
ACVM Registered
2010-11-12
LEVENTA 30 mL – Leaflet, Carton and Label A010426 Page 1 of 6 LEVENTA 17-May-23 Leaflet RESTRICTED VETERINARY MEDICINE KEEP OUT OF REACH OF CHILDREN FOR ANIMAL TREATMENT ONLY LEVENTA ® LEVOTHYROXINE SODIUM 1 MG/ML ORAL SOLUTION FOR DOGS. COMPOSITION LEVENTA is an oral solution containing 1 mg/mL levothyroxine sodium (as multihydrate) (equivalent to 0.97 mg levothyroxine) and 15% v/v ethanol as preservative. INDICATIONS Treatment of hypothyroidism in dogs. DIRECTIONS FOR USE For oral use. Once opened, use within 6 months. DOSAGE AND ADMINISTRATION The clinical diagnosis of hypothyroidism should be confirmed by laboratory tests. In thyroid hormone replacement therapy with levothyroxine, the dose rate and regimen have to be tailored individually to each dog. A starting dose rate of 20 μg levothyroxine sodium/kg (0.2 mL per 10 kg body weight) once daily is recommended. Four weeks later, dose adjustment should be performed based on the clinical response to treatment and thyroid hormone concentration evaluation 4-6 hours after administration of the product. Further assessment of hormone responses and dose adjustment may be repeated at 4 week intervals if required. A maintenance dose rate between 10 and 40 μg/kg body weight (0.1 – 0.4 mL/10 kg body weight) once-daily is generally sufficient. The dosage suitable to treat your dog is decided by your prescribing veterinarian. Depending on the dosage and the body weight of the dog, the volume (in mL) of the product to be administered once-daily can be calculated using the following table. BODY WEIGHT (KG) DOSAGE (UG/KG) 10 20 30 40 VOLUME OF THE PRODUCT (ML) 5 0.05 0.10 0.15 0.20 10 0.10 0.20 0.30 0.40 15 0.15 0.30 0.45 0.60 20 0.20 0.40 0.60 0.80 25 0.25 0.50 0.75 1.00 30 0.30 0.60 0.90 1.20 35 0.35 0.70 1.05 1.40 40 0.40 0.80 1.20 1.60 45 0.45 0.90 1.35 1.80 50 0.50 1.00 1.50 2.00 The dose for dogs weighing more than 50 kg should be calculated according to body weight in the same way. Once a suitable dose rate and regimen have been established, it is recommended to Leia o documento completo